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PDE4C

From Wikipedia, the free encyclopedia
PDE4C
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPDE4C, DPDE1, phosphodiesterase 4C, PDE21
External IDsOMIM: 600128; MGI: 99556; HomoloGene: 20256; GeneCards: PDE4C; OMA:PDE4C - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_201607
NM_001310465

RefSeq (protein)

NP_000914
NP_001092288
NP_001092289
NP_001317101
NP_001356630

NP_001297394
NP_963901

Location (UCSC)Chr 19: 18.21 – 18.25 MbChr 8: 71.18 – 71.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

cAMP-specific 3',5'-cyclic phosphodiesterase 4C is an enzyme that in humans is encoded by the PDE4C gene.[5]


Tissue localisation

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PDE4C is predominantly found in peripheral tissues.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105650Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031842Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: PDE4C phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)".
  6. ^ Zhang, HT (2009). "Cyclic AMP-Specific Phosphodiesterase-4 as a Target for the Development of Antidepressant Drugs". Current Pharmaceutical Design. 15 (14): 1688–1698. doi:10.2174/138161209788168092. PMID 19442182.

Further reading

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[edit]
  • Overview of all the structural information available in the PDB for UniProt: Q08493 (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) at the PDBe-KB.