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POLR2H

From Wikipedia, the free encyclopedia

POLR2H
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPOLR2H, RPABC3, RPB17, RPB8, polymerase (RNA) II subunit H, RNA polymerase II subunit H, RNA polymerase II, I and III subunit H
External IDsOMIM: 606023; MGI: 2384309; HomoloGene: 4540; GeneCards: POLR2H; OMA:POLR2H - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_145632
NM_001356423

RefSeq (protein)

NP_663607
NP_001343352

Location (UCSC)Chr 3: 184.36 – 184.37 MbChr 16: 20.54 – 20.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DNA-directed RNA polymerases I, II, and III subunit RPABC3 is a protein that in humans is encoded by the POLR2H gene.

This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.[5]

Interactions

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POLR2H has been shown to interact with POLR2C,[6] POLR2G,[6] POLR2A,[6] POLR2B[6] and POLR2E.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163882Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021018Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: POLR2H polymerase (RNA) II (DNA directed) polypeptide H".
  6. ^ a b c d e Acker J, de Graaff M, Cheynel I, Khazak V, Kedinger C, Vigneron M (July 1997). "Interactions between the human RNA polymerase II subunits". J. Biol. Chem. 272 (27). UNITED STATES: 16815–21. doi:10.1074/jbc.272.27.16815. ISSN 0021-9258. PMID 9201987.

Further reading

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