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PSRC1

From Wikipedia, the free encyclopedia
PSRC1
Identifiers
AliasesPSRC1, DDA3, FP3214, proline and serine rich coiled-coil 1
External IDsOMIM: 613126; MGI: 1913099; HomoloGene: 49603; GeneCards: PSRC1; OMA:PSRC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001190161
NM_019976

RefSeq (protein)

NP_001177090
NP_064360

Location (UCSC)Chr 1: 109.28 – 109.28 MbChr 3: 108.29 – 108.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Proline/serine-rich coiled-coil protein 1 is a protein that in humans is encoded by the PSRC1 gene.[5][6][7]

This gene encodes a proline-rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134222Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068744Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lo PK, Wang FF (Nov 2002). "Cloning and characterization of human and mouse DDA3 genes". Biochim Biophys Acta. 1579 (2–3): 214–8. doi:10.1016/s0167-4781(02)00512-2. PMID 12427559.
  6. ^ Lo PK, Chen JY, Lo WC, Chen BF, Hsin JP, Tang PP, Wang FF (Feb 2000). "Identification of a novel mouse p53 target gene DDA3". Oncogene. 18 (54): 7765–74. doi:10.1038/sj.onc.1203167. PMID 10618717.
  7. ^ a b "Entrez Gene: PSRC1 proline/serine-rich coiled-coil 1".

Further reading

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