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Phosphoglycerate kinase (GTP)

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phosphoglycerate kinase (GTP)
Identifiers
EC no.2.7.2.10
CAS no.62213-34-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins

In enzymology, a phosphoglycerate kinase (GTP) (EC 2.7.2.10) is an enzyme that catalyzes the chemical reaction

GTP + 3-phospho-D-glycerate GDP + 3-phospho-D-glyceroyl phosphate

Thus, the two substrates of this enzyme are GTP and 3-phospho-D-glycerate, whereas its two products are GDP and 3-phospho-D-glyceroyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is GTP:3-phospho-D-glycerate 1-phosphotransferase.

References

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  • Reeves RE, South DJ (1974). "Phosphoglycerate kinase (GTP). An enzyme from Entamoeba histolytica selective for guanine nucleotides". Biochem. Biophys. Res. Commun. 58 (4): 1053–7. doi:10.1016/S0006-291X(74)80250-0. PMID 4365563.