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Plasmodium RUF4 RNA

From Wikipedia, the free encyclopedia
Plasmodium RNA of unknown function 4
Predicted secondary structure of RUF4
Identifiers
SymbolRUF4
RfamRF01578
Other data
RNA typesRNA
Domain(s)Plasmodium
PDB structuresPDBe

RUF4 is a non-coding RNA (ncRNA) present within the plasmodium genome. Bioinformatic studies predicted that RUF4 was present within the plasmodium genome and the expression of this ncRNA was verified by Northern Blot.[1] The location of this ncRNAs was subsequently mapped within the P. falciparum strain 3DF genome by primer extension. RUF4 is a novel RNA of unknown function but has shown to contain some structural similarity with the H/ACA box snoRNA but no known targets have been identified.

References

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  1. ^ Chakrabarti K, Pearson M, Grate L, Sterne-Weiler T, Deans J, Donohue JP, Ares M (November 2007). "Structural RNAs of known and unknown function identified in malaria parasites by comparative genomics and RNA analysis" (Free full text). RNA. 13 (11): 1923–1939. doi:10.1261/rna.751807. PMC 2040097. PMID 17901154.
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