Plexiform fibrohistiocytic tumor

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Plexiform fibrohistiocytic tumor
SpecialtyDermatology

Plexiform fibrohistiocytic tumor is a rare tumor that arises primarily on the upper extremities of children and young adults.[1]: 612 

Signs and symptoms[edit]

Plexiform fibrohistiocytic tumor appears as a painless, slowly expanding soft tissue mass located in the dermis and subcutis.[2] The skin layer above is somewhat elevated and occasionally has a central depression.[3] The upper extremities were more commonly affected by plexiform fibrohistiocytic tumors. It was most frequently found on the fingers, hand, or wrist.[4] The tumour's dimensions vary from 0.3 to 8.5 cm.[2]

Causes[edit]

Plexiform fibrohistiocytic tumor's pathogenesis is unclear.[2] A few cases of prior trauma have been documented.[3] Two series of congenital instances have been documented.[5][6]

See also[edit]

References[edit]

  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. ^ a b c Taher, Altaf; Pushpanathan, Chitra (2007-07-01). "Plexiform Fibrohistiocytic Tumor: A Brief Review". Archives of Pathology & Laboratory Medicine. 131 (7): 1135–1138. doi:10.5858/2007-131-1135-PFTABR. ISSN 1543-2165.
  3. ^ a b Enzinger, Franz M.; Zhang, Renyuan (1988). "Plexiform Fibrohistiocytic Tumor Presenting in Children and Young Adults". The American Journal of Surgical Pathology. 12 (11). Ovid Technologies (Wolters Kluwer Health): 818–826. doi:10.1097/00000478-198811000-00002. ISSN 0147-5185.
  4. ^ Remstein, Ellen D.; Arndt, Carola A.S.; Nascimento, Antonio G. (1999). "Plexiform Fibrohistiocytic Tumor: Clinicopathologic Analysis of 22 Cases". The American Journal of Surgical Pathology. 23 (6). Ovid Technologies (Wolters Kluwer Health): 662–670. doi:10.1097/00000478-199906000-00005. ISSN 0147-5185.
  5. ^ HOLLOWOOD, K.; HOLLEY, M.P.; FLETCHER, C.D.M. (1991). "Plexiform fibrohistiocytic tumour: clinicopathological, immunohistochemical and ultrastructural analysis in favour of a myofibroblastic lesion". Histopathology. 19 (6). Wiley: 503–513. doi:10.1111/j.1365-2559.1991.tb01498.x. ISSN 0309-0167.
  6. ^ Leclerc, Stéphanie; Hamel‐Teillac, Dominique; Oger, Patrice; Brousse, Nicole; Fraitag, Sylvie (2005-08-18). "Plexiform fibrohistiocytic tumor: three unusual cases occurring in infancy". Journal of Cutaneous Pathology. 32 (8). Wiley: 572–576. doi:10.1111/j.0303-6987.2005.00334.x. ISSN 0303-6987.