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Proteo-phage-1 RNA motif

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Proteo-phage-1
Consensus secondary structure and sequence conservation of Proteo-phage-1 RNA
Identifiers
SymbolProteo-phage-1
RfamRF03044
Other data
RNA typeGene; sRNA
SOSO:0001263
PDB structuresPDBe

The Proteo-phage-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] Energetically stable tetraloops often occur in this motif.

Proteo-phage-1 motif RNAs are found in Pseudomonadota. Nearby to most Proteo-phage-1 motif RNAs are genes that are typical of phages. This, in turn, suggests that Proteo-phage-1 motif RNAs are found in prophages, and presumably also used by phage particles, although Proteo-phage-1 motif RNAs have not been observed in genome sequences of purified phages. It is ambiguous whether Proteo-phage-1 RNAs function as cis-regulatory elements or whether they operate in trans.

References[edit]

  1. ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.