Jump to content

RCBTB2

From Wikipedia, the free encyclopedia

RCBTB2
Identifiers
AliasesRCBTB2, CHC1L, RLG, RCC1 and BTB domain containing protein 2
External IDsOMIM: 603524; MGI: 1917200; HomoloGene: 970; GeneCards: RCBTB2; OMA:RCBTB2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001170694
NM_134083

RefSeq (protein)

NP_001164165
NP_598844

Location (UCSC)Chr 13: 48.49 – 48.53 MbChr 14: 73.36 – 73.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RCC1 and BTB domain-containing protein 2 is a protein that in humans is encoded by the RCBTB2 gene.[5][6]

This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.[6]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000136161Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022106Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Devilder MC, Cadoret E, Cherel M, Moreau I, Rondeau G, Bezieau S, Moisan JP (Jan 1999). "cDNA cloning, gene characterization and 13q14.3 chromosomal assignment of CHC1-L, a chromosome condensation regulator-like guanine nucleotide exchange factor". Genomics. 54 (1): 99–106. doi:10.1006/geno.1998.5498. PMID 9806834.
  6. ^ a b "Entrez Gene: RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2".

Further reading

[edit]