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Protein-coding gene in the species Homo sapiens
RPS26 Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0 , 4V6X , 5A2Q , 5AJ0 , 5FLX , 3J7R , 4D61 , 4D5L , 4UJD , 3J7P , 4UJE , 4UJC
Identifiers Aliases RPS26 , DBA10, S26, ribosomal protein S26, eS26External IDs OMIM : 603701 ; MGI : 1351628 ; HomoloGene : 37420 ; GeneCards : RPS26 ; OMA :RPS26 - orthologs Wikidata
40S ribosomal protein S26 is a protein that in humans is encoded by the RPS26 gene .[5] [6] [7]
Function [ edit ]
Ribosomes , the organelles that catalyze protein synthesis , consist of a small 40S subunit and a large 60S subunit . Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. It is located in the cytoplasm . As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]
References [ edit ]
^ a b c GRCh38: Ensembl release 89: ENSG00000197728 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025362 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes" . Genome Res . 8 (5): 509–23. doi :10.1101/gr.8.5.509 . PMID 9582194 .
^ Filipenko ML, Mishin VP, Suturina IuA, Muravlev AI, Kopantsev EA, Karpova GG, Mertvetsov NP (Aug 1996). "[Mapping of the genes for ribosomal proteins S26, L19, and L32 on human chromosomes]". Bioorg Khim . 21 (11): 838–44. PMID 8670309 .
^ a b "Entrez Gene: RPS26 ribosomal protein S26" .
Further reading [ edit ]
Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol . 73 (11–12): 933–47. doi :10.1139/o95-101 . PMID 8722009 .
Filipenko ML, Vladimirov SN, Muravlev AI, et al. (1994). "[Cloning cDNA of human S26 ribosomal protein and determination of its primary structure]". Bioorg. Khim . 20 (6): 644–9. PMID 7945460 .
Vincent S, Marty L, Fort P (1993). "S26 ribosomal protein RNA: an invariant control for gene regulation experiments in eucaryotic cells and tissues" . Nucleic Acids Res . 21 (6): 1498. doi :10.1093/nar/21.6.1498 . PMC 309346 . PMID 8464749 .
Vladimirov SN, Ivanov AV, Karpova GG, et al. (1996). "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry" . Eur. J. Biochem . 239 (1): 144–9. doi :10.1111/j.1432-1033.1996.0144u.x . PMID 8706699 .
Filipenko ML, Vinichenko NA, Karpova GG, et al. (1998). "Isolation, structural analysis and mapping of the functional gene of human ribosomal protein S26". Gene . 211 (2): 287–92. doi :10.1016/S0378-1119(98)00108-5 . PMID 9602156 .
Xu XR, Huang J, Xu ZG, et al. (2002). "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver" . Proc. Natl. Acad. Sci. U.S.A . 98 (26): 15089–94. doi :10.1073/pnas.241522398 . PMC 64988 . PMID 11752456 .
Ivanov AV, Malygin AA, Karpova GG (2002). "[Ribosomal protein binding with the first intron of the human ribosomal protein S26 pre-mRNA stimulates its interaction with proteins extracted from Hela cells]". Mol. Biol. (Mosk.) . 36 (3): 503–10. PMID 12068637 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Ivanov AV, Malygin AA, Karpova GG (2005). "Human ribosomal protein S26 suppresses the splicing of its pre-mRNA". Biochim. Biophys. Acta . 1727 (2): 134–40. doi :10.1016/j.bbaexp.2004.12.011 . PMID 15716004 .
Yu Y, Ji H, Doudna JA, Leary JA (2005). "Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes" . Protein Sci . 14 (6): 1438–46. doi :10.1110/ps.041293005 . PMC 2253395 . PMID 15883184 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 . PMID 17081983 . S2CID 7827573 .
Tu LC, Yan X, Hood L, Lin B (2007). "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells" (PDF) . Mol. Cell. Proteomics . 6 (4): 575–88. doi :10.1074/mcp.M600249-MCP200 . PMID 17220478 . S2CID 7203032 .
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 . PMID 17353931 .
External links [ edit ]