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STEAP1

From Wikipedia, the free encyclopedia
STEAP1
Identifiers
AliasesSTEAP1, PRSS24, STEAP, six transmembrane epithelial antigen of the prostate 1, STEAP family member 1
External IDsOMIM: 604415; MGI: 1917608; HomoloGene: 8256; GeneCards: STEAP1; OMA:STEAP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012449

NM_027399

RefSeq (protein)

NP_036581

NP_081675

Location (UCSC)Chr 7: 90.15 – 90.16 MbChr 5: 5.79 – 5.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Metalloreductase STEAP1 is an enzyme that in humans is encoded by the STEAP1 gene.[5]

This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164647Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015652Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: STEAP1 six transmembrane epithelial antigen of the prostate 1".

Further reading

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