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Salutaridine reductase (NADPH)

From Wikipedia, the free encyclopedia
salutaridine: NADPH 7-oxidoreductase
Identifiers
EC no.1.1.1.248
CAS no.152743-95-8
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IntEnzIntEnz view
BRENDABRENDA entry
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MetaCycmetabolic pathway
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In enzymology, a salutaridine reductase (NADPH) (EC 1.1.1.248) is an enzyme that catalyzes the chemical reaction

salutaridinol + NADP+ salutaridine + NADPH + H+

Thus, the two substrates of this enzyme are salutaridinol and NADP+, whereas its 3 products are salutaridine, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is salutaridinol:NADP+ 7-oxidoreductase. This enzyme participates in alkaloid biosynthesis i.

References

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  • Gerady R, Zenk MH (1993). "Purification and characterization of salutaridine:NADPH 7-oxidoreductase from Papaver somniferum". Phytochemistry. 34 (1): 125–132. doi:10.1016/S0031-9422(00)90793-3.