"Setting the World on Fire" debuted at number 26 on the Australian Singles Chart, becoming Chesney's first ever song to chart in Australia.
In Canada, the song debuted at number 47 on the Canada Country chart and has reached number one and debuted at number 67 on the Canadian Hot 100 and peaked at number 48.
In the United States, the song sold 93,000 copies during its first week, marking Chesney's biggest sales week for a single, surpassing the previous best sales week of his 2012 hit "Feel Like a Rock Star".[4] It was the second best-selling song for the week of August 20, 2016. It concurrently debuted at number 29 on the US Billboard Hot 100, becoming Chesney's twenty-fifth top 40 hit on the all-genre chart. It also rose from number 43 to number two on Hot Country Songs chart, eventually peaking at number one. On the Country Airplay chart, it debuted at number 22 and has reached number one. "Setting the World on Fire" debuted at number 35 on the Adult Pop Songs chart for the week of October 8, 2016 and is Chesney's first entry on the chart.[5]
As of January 2017, it has sold 624,000 copies in the United States.[6]
The music video was directed by P. R. Brown, and premiered in September 2016. Neither Chesney nor Pink are featured in the music video, except for various posters and billboards displaying the collaboration. The music video is in black and white, and tells the story of two young lovers who move to Los Angeles and have a romantic encounter, as described in the song's lyrics. It was filmed around Los Angeles and Riverside, California over two days in August 2016.[7]