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TNFAIP1

From Wikipedia, the free encyclopedia
TNFAIP1
Identifiers
AliasesTNFAIP1, B12, B61, BTBD34, EDP1, hBACURD2, TNF alpha induced protein 1
External IDsOMIM: 191161; MGI: 104961; HomoloGene: 22519; GeneCards: TNFAIP1; OMA:TNFAIP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021137

NM_001159392
NM_009395

RefSeq (protein)

NP_066960

NP_001152864
NP_033421

Location (UCSC)Chr 17: 28.34 – 28.35 MbChr 11: 78.41 – 78.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1 gene.[5][6][7]

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000109079Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017615Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Dixit VM, Green S, Sarma V, Holzman LB, Wolf FW, O'Rourke K, Ward PA, Prochownik EV, Marks RM (Mar 1990). "Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin". J Biol Chem. 265 (5): 2973–8. doi:10.1016/S0021-9258(19)39896-5. PMID 2406243.
  6. ^ Holzman LB, Marks RM, Dixit VM (Dec 1990). "A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein". Mol Cell Biol. 10 (11): 5830–8. doi:10.1128/MCB.10.11.5830. PMC 361366. PMID 2233719.
  7. ^ a b "Entrez Gene: TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)".

Further reading

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