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TSR2 (gene)

From Wikipedia, the free encyclopedia
TSR2
Identifiers
AliasesTSR2, DT1P1A10, WGG1, DBA14, ribosome maturation factor, TSR2 ribosome maturation factor
External IDsOMIM: 300945; MGI: 1916749; HomoloGene: 43235; GeneCards: TSR2; OMA:TSR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001346789
NM_001346790
NM_001346791
NM_001346792
NM_058163

NM_001164578
NM_175146

RefSeq (protein)

NP_001333718
NP_001333719
NP_001333720
NP_001333721
NP_477511

NP_001158050
NP_780355

Location (UCSC)Chr X: 54.44 – 54.45 MbChr X: 149.87 – 149.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TSR2 ribosome maturation factor is a protein that in humans is encoded by the TSR2 gene. [5]

Function

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The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000158526Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025264Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: TSR2 ribosome maturation factor". Retrieved 2020-04-12.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.