Talk:Atovaquone

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Untitled

What is the correct structure for Atovaquone? I have seen two different versions, one with the carbonyl groups in the 1 and 4 positions, and another with them in the 1 and 2 positions (the hydroxy group being switched from 2 to 4 in the latter). PubChem actually shows the structure of one version, and the IUPAC name of the other. I will correct the name to describe the former, which is the one pictured on the Wikipedia article. Does anyone have any definitive evidence as to the true structure (and hence the true name) of the molecule? Ngoshn (talk) 18:14, 2 September 2009 (UTC)[reply]

Perhaps in reality the drug exists as a mixture of these two forms in equilibrium?Ngoshn (talk) 18:05, 2 September 2009 (UTC)[reply]

Um... Hallucinations?

Not only have I heard that hallucinations is a side effect of this drug, I hallucinated on it, while using it to prevent malaria. And plus, the time when the hallucinations were most powerful was right when the drug was supposed to peak. Trust me, they were powerful. Good thing I was alone when it kicked in. I would NOT have been able to be around people.

Anyways, I'm going to look for a source to I can add it to "side effects".

MarthsBullet (talk) 20:54, 30 October 2010 (UTC)[reply]

method of action

How does atovaquone work? --98.70.52.179 (talk) 15:07, 22 February 2011 (UTC) It inhibits complex III of the mitochondrial electron transport chain; hence, it is an inhibitor of respiration. Philip Jewess — Preceding unsigned comment added by 93.191.24.30 (talk) 15:26, 27 January 2016 (UTC)[reply]

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Starting clinical studies for cancer

Old Malaria Drug May Have New Role Fighting Cancer. July 2016 may sensitise cancer to radiotherapy. - Rod57 (talk) 02:55, 24 January 2017 (UTC)[reply]