Jump to content

Talk:Bortezomib

Page contents not supported in other languages.
From Wikipedia, the free encyclopedia

"Cancer-drug refund scheme..."

[edit]

Is it appropriate to add details of this BBC article: [1], the implications of which are that this drug is acting as a test case for a licencing deal which will open the doors to the prescription of many other expensive drugs in treatment of UK patients? ddvmor 12:10, 5 June 2007 (UTC)[reply]

Formula?

[edit]

How can the chemical formula be correct in the info box when it doesn't include a Boron atom? Can someone please calculate the molecular formula and fix this? 67.93.205.78 13:20, 12 October 2007 (UTC)[reply]

checkY Done. The {{Drugbox}} template didn't have a parameter for boron in the formula. Fvasconcellos (t·c) 16:51, 12 October 2007 (UTC)[reply]

Structure

[edit]

The structure drawing is wrong. It doesn't show the two nitrogens in the pyrazine ring. —Preceding unsigned comment added by 66.92.19.253 (talk) 17:45, 15 October 2008 (UTC)[reply]

Someone seems to have fixed it now. Rod57 (talk) 01:01, 11 February 2009 (UTC)[reply]

Can someone elaborate about the Nobel price awarded research of Chemistry 2004 by Aaron Chanover, Avram Hershko from Israel and Irwin Rose from USA "for the discovery of ubiquitin-mediated protein degradation"' That led to the development of this landmark drag —Preceding unsigned comment added by 217.132.71.171 (talk) 06:11, 2 July 2010 (UTC)[reply]

millennium aquired velcade through an aquisition of COR theraputics, not Leukosite

[edit]

millennium aquired velcade through an aquisition of COR theraputics, not Leukosite — Preceding unsigned comment added by 76.119.89.49 (talk) 03:47, 3 December 2011 (UTC)[reply]

as a non-expert reading this sentence:

This changed significantly when one of the first volunteers to
receive the drug in the clinical trial achieved a
[http://www.myelomaonline.org.uk/NetCommunity/Page.aspx?&pid=439&srcid=437
complete response] and was still alive four years later.

i expect "complete response" to link to an explanation of the term, but instead it links to a (404'd) external page. i think the external link should be put into a footnote (and updated, if possible), and an link to an explanation of "complete response" provided instead. the best i found was: Response_rate_ratio, but that can't apply here (to a single patient), as it refers to a rate of members within a group.

83.236.58.48 (talk) 01:21, 12 March 2012 (UTC)[reply]

The article states "The boron atom in bortezomib binds the catalytic site of the 26S proteasome[6] with high affinity and specificity," but the article that is cited doesn't state anything about the boron actually doing the attacking. Additional sources are needed or the article needs edited. — Preceding unsigned comment added by 128.163.7.133 (talk) 13:31, 20 October 2014 (UTC)[reply]

[edit]

Hello fellow Wikipedians,

I have just modified 3 external links on Bortezomib. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

When you have finished reviewing my changes, please set the checked parameter below to true or failed to let others know (documentation at {{Sourcecheck}}).

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

  • If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
  • If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 08:13, 6 November 2016 (UTC)[reply]

[edit]

Hello fellow Wikipedians,

I have just modified 3 external links on Bortezomib. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

  • If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
  • If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 19:09, 23 July 2017 (UTC)[reply]