Talk:Cardiac transient outward potassium current

Physiology Mid‑importance

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Molecular Biology: MCB

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Just a note[edit]

I have no idea what a single sentence in this article means. It really needs a layman's explanation. -mattbuck (Talk) 10:43, 15 August 2013 (UTC)[reply]

Another note: I find some statements misleading.

'This outward flow of positively charged ions constitutes the Ito1 and causes the transmembrane voltage to decrease.This decrease of the transmembrane potential is known as repolarization'

Actually, the transmembrane voltage is high in the resting cell, even higher with hyperpolarized cell membrane, decreases (roughly to 0) during the action potential (this is called depolarization) and its return to the higher, resting values is called repolarization. So one can say that Ito1 decreases the action potential or depolarization, but this effect actually means an increase in transmembrane voltage. Pharmacologist — Preceding unsigned comment added by 193.6.63.109 (talk) 15:11, 21 May 2014 (UTC)[reply]

The transmembrane voltage in a resting cell is low, about -70mV. Depolarization therefore increases the membrane potential to zero or even higher. Outwar currents of potassium then repolarizes a cell to its resting potential.--Bioscan (talk) 14:26, 16 March 2018 (UTC)[reply]