Talk:Human papillomavirus infection/Archive 3

Removing outdated material

JDowning, regarding this and this, be sure that what the sources are covering is actually outdated. Yes, we follow WP:MEDDATE, but WP:MEDDATE's main focus is on whether or not material is no longer current knowledge. If the content is still current knowledge, then the source is essentially up-to-date. For material that is still current knowledge, there is no need whatsoever to replace older sources with newer sources...except for showing readers that the material is supported by newer sources. In that latter edit, you stated, "info appears to be out-of-date, at least in US and UK" and pointed to this and this source. But we need to consider more than just the U.S. and the UK. Also keep in mind that while the Centers for Disease Control and Prevention (CDC) is a great source, it's a public health institute of the United States. By contrast, the World Health Organization (WHO) is concerned with international public health. If you reply to me on this, I ask that you don't ping me. Flyer22 Reborn (talk) 21:40, 7 February 2019 (UTC)

The two edits I pointed to are concerned with the U.S., though. One piece is a sentence concerning the United States. The other is a paragraph that begins with a statement about the United States. So focusing on sources about the U.S. for that material is obviously fine. Flyer22 Reborn (talk) 21:47, 7 February 2019 (UTC)

My edits for the WHO reference were out-of-sequence ... it was being used for a single, now out-of-date statement: "In the United States, HPV is expected to replace tobacco as the main causal agent for oral cancer, and the number of newly diagnosed, HPV-associated head and neck cancers is expected to surpass that of cervical cancer cases by 2020."

This has already occurred. I'd updated the statement but accidentally left the WHO reference, which I deleted later. JDowning (talk) 22:07, 7 February 2019 (UTC)

As an additional note, many of the infection-rate references are/were more than a decade old, and the statistics have changed massively over time--for example the number of HPV-associated Oropharyngeal cancers has more than doubled[1] in the US male population. I am working through the article looking for such out-of-date statistics, and replacing them. JDowning (talk) 22:25, 7 February 2019 (UTC)

Cure?

Sources insufficient "Dr. Eva Ramón Gallegos of National Polytecnic Institute in Mexico cured HPV with photodynamic therapy and 5-Aminolevulinic acid. The compound is accumulated in HPV-infected cells. Thereafter, the light destroys the infected cells and may trigger an immune response against them." Doc James (talk · contribs · email) 06:50, 28 February 2019 (UTC)

References

Fake picture

Someone inserted a fake picture of the HPV virus designed to look like a Jewish Star. It is fake. — Preceding unsigned comment added by 2601:646:8C00:CE00:5D12:BC5F:7261:580A (talk) 19:28, 4 June 2019 (UTC)

No, that's real. Its' a fairly simple geometric shape composed of six units around a center. Thank you for your concern, though. DS (talk) 00:03, 5 June 2019 (UTC)

I don't think this is correct. It's labelled as SV40 large T antigen helicase domain in the linked source, though there's a slightly different picture there. I didn't think HPV has large T antigen? Pinging @Doc James and Opabinia regalis: for an opinion. Espresso Addict (talk) 07:26, 11 July 2019 (UTC)

This source supports it appears.[2] Doc James (talk · contribs · email) 15:49, 11 July 2019 (UTC)

The image is a real protein and nothing to do with Jewish anything, but I think Espresso Addict is right that it's misplaced on this particular article. I don't see a source anywhere that HPV has a large T antigen - see the genome map here. I believe that protein is specific to polyomaviruses; E6 and maybe E7 are the HPV oncoproteins IIRC. It's probably confusion left over from when papilloma and polyoma viruses were classified together as papovaviruses. I think the commons category name is wrong too. The micrograph of a virus particle seems like a suitable replacement lead image (and looks correct), or there's structures in the PDB of the actual HPV capsid that I don't have time to make an image from right now but could this weekend. Opabinia regalis (talk) 06:57, 12 July 2019 (UTC)

Doc James: Indeed, that was what I was looking at.

Thanks, Opabinia regalis. I haven't worked on papillomaviruses for so many years that I thought perhaps they'd discovered a large T antigen analogue while I wasn't looking! I think the commons categories might well be at fault. I've swapped with the em from the Virology section. If you could make an image of the HPV oncoproteins E7/E6 or the capsid that would be very nice. Espresso Addict (talk) 07:28, 12 July 2019 (UTC)

Heh, turns out that rendering a whole capsid is a big ask for a Macbook Air :) I'll give it a shot on my other computer this week. Opabinia regalis (talk) 08:16, 15 July 2019 (UTC)

Done! Opabinia regalis (talk) 07:07, 20 July 2019 (UTC)

One more post here - I think I figured out the source of the error. The commons category was created via automated import from SCOP, which also contains this error. Since SCOP stopped updating in 2009, they're not going to fix it, so I nominated the commons category for deletion. Opabinia regalis (talk) 19:13, 21 July 2019 (UTC)

Foundations 2 Group 4b Goals

Our goals group for editing this article are to find updated and accurate infection rates of HPV and to update with current guidelines for treatment of HPV infection. Niamh.ogrady (talk) 20:48, 30 July 2019 (UTC)

Please make sure that all your group members assign themselves to this article before making individual edits. Thanks. Health policy (talk) 04:12, 31 July 2019 (UTC)

Peer Review

Although the group did not provide an update for specific HPV treatment,  edits added helped provide great information on further risks of certain cancers for those with the HPV infection. The group was also able provide more updated information on screening and mouth testing to help improve the article. Information added was given in a neutral tone and well-cited. --Elizabeth Hays (talk) 21:15, 5 August 2019 (UTC)

Part 2: Are the points included verifiable with cited secondary sources that are freely available?

Yes, the group used reliable sources such as reviews and comprehensive meta-analysis to provide their information.

YooCo (talk) 22:04, 5 August 2019 (UTC)

Part 2: Are the edits formatted consistent with Wikipedia's manual of style? Yes, the editor provided adequate and reliable sources for new information added to the article. The section on genital cancers was renamed to anal cancer, and a new section on penile cancer was generated and properly sourced by the editor. The revisions are easy to follow and include links to relevant wikipedia articles. Aoka222 (talk) 04:55, 6 August 2019 (UTC)

Part 2: Is there any evidence of plagiarism or copyright violation? If yes, specify…

There is no evidence of plagiarism or copyright violation.

Diagnosis section

I count five different brand names of tests name-checked in the diagnosis section; I propose removing them all and consolidating the section. I also suggest consolidating the detailed study summaries in this section ("One small study used" ... "In one study researchers sampled" ... "In one study the subjects were asked"). Making these changes would reduce the length of the section by about half. Thoughts? JDowning (talk) 00:58, 8 February 2019 (UTC)

I am going to remove the information about brand names of HPV tests and provide further information on current guidelines on when the testing is indicated Niamh.ogrady (talk) 17:52, 6 August 2019 (UTC)

Screening

Is a method for diagnosis. Do not really need both in the heading. Doc James (talk · contribs · email) 20:45, 9 August 2019 (UTC)

"Signs and symptoms"

Not sure what is wrong with this heading? Doc James (talk · contribs · email) 08:19, 12 October 2019 (UTC)

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 1 July 2019 and 23 August 2019. Further details are available on the course page. Student editor(s): Niamh.ogrady, Jdinger123, Arcmelodia, JasperT888.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 23:59, 16 January 2022 (UTC)