Talk:Paolo Macchiarini

Untitled

I've been cleaning up some material and noticed the first few paragraphs are a bit boring.

This is one that I find a bit too technical for the encyclopedia: "Macchiarini's interests include extended surgery for lung, esophageal, and mediastinal tumors; adult and pediatric tracheal surgery; lung and heart-lung transplantation; pulmonary endarterectomy; (bio)artificial lung; and experimental research, education, training."

I'm going to delete it. There is a lot more of interest to say and rather focus on the groundbreaking or controversial matters in his work.

Canadianknowledgelover (talk) 08:57, 29 June 2014 (UTC)

First groundbreaking operation - expanding section. Detail about birthplace.

I'm going to expand the part of the first groundbreaking operation on Castillo. This is what it says now: "In 2008 he performed the first Adult stem cell grown trachea transplant on patient Claudia Castillo.[3][4][5]"

I also looked at the references. Two are pretty good articles, but the Science Daily is just repetitive of other things and also worded in a technical manner that may be off-putting to many. In case anyone wants to look at it, this is the citation: "Adult Stem Cell Breakthrough: First Tissue-Engineered Trachea Successfully Transplanted" Science Daily, November 18, 2008. I found some more references that I will add.

I added subheadings for the surgeries as they were getting too jumbled together. In doing so, I titled a new heading for the "history-making surgeries performed". As I was listing them out, I noticed a line about a couple that were starting to sound routine, so I deleted that note. This is it if anyone still wants to go back: "In June 2012 Macchiarini transplanted a synthetic trachea and cricoid (a part of the larynx) in two patients at Krasnodar University in Russia."

I added a couple of other headings and changed the Education and History section to just read Education. History was getting too long and needed breaking down.

Yesterday I added Macchiarini's date and place of birth, with citation. Today I also changed the part of the education section that said he studied at "his homeland" of Italy. Italy is not the country of his birth. See also the Lancet article provided by another editor about experiences with Italy and feeling more like a "citizen of the world" than attached to a particular nation: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60382-1/fulltext.

Canadianknowledgelover (talk) 06:31, 30 June 2014 (UTC)

Expanding section about operation on first child

I'm going to expand the section talking about the first child to receive stem cell therapy. Right now it says: "The first successful operation on a child using the child's own stem cells on a donated trachea followed in March 2010." I will use the reference provided and add several others.

Canadianknowledgelover (talk) 04:11, 2 July 2014 (UTC)

Defamatory content

The section 'scientific misconduct' contains defamatory claims, posted by the same people who made the accusations of scientific misconduct against Prof Macchiarini (as revealed by the geographical location of the IP address used to edit). Attempts made to correct the defamatory claims, with correctly referenced material, have been replaced persistently by the accusers, in violation of Wikipedia guidelines. Although the accusations of scientific misconduct were indeed made, and widely reported, they were all dismissed after full investigation and hence the accusers' attempts to use Wikipedia to repeat them in detail and further their personal vendetta should surely not be allowed.

This is the suggested corrected wording:

Scientific misconduct

In 2012 Prof. Macchiarini was accused by Italian legal authorities of demanding money from patients for preferential treatment, and was placed under house arrest.[25] These accusations were thrown out of court in June 2015 [pdf of Italian court proceedings acts as reference]. That year Professor Macchiarini also retracted a scientific paper due to the accidental mis-citation of a table[26] but any question of intentional misconduct was dismissed [Pdf of Karolinska Institutet decision 8081/12-609]

In 2014, a group of ex-collaborators accused Prof Macchiarini of misconduct regarding a series of 7 papers, after one of their number had been found guilty of plagiarism of Macchiarini's team's research [Karolinska Institutet decision 2-1309/2014 see p4/7 of Karolinska press release on Science website]

The accusations were leaked to the press and to internet sources, including confidential patient records, resulting in press coverage of the enquiry. Prof Macchiarini has spoken out strongly against this breach of confidentiality [Retraction Watch statement].

After Karolinska Institutet launched an internal investigation and a thorough analysis of the publications and medical records of the patients, the Vice Chancellor dismissed all the allegations. [Karolinska Institutet press releaseThe Lancet vol 386 iss 9997, p932, 5th Sept 2015 ]

References

I am not involved in this dispute, and do not intend to become so. But I will point out that the outcome is likely to depend on the quality of the references provided. References should be to reliable independent published sources. A pdf is not a published source. Macchiarini's own home page is not an independent source. A reference to The Lancet is excellent – but should include a date, issue number, and page number, so that other editors and readers can verify it. Maproom (talk) 09:58, 15 November 2015 (UTC)

Thanks Maproom. I entirely agree - the ref to Macchiarini's homepage was from further up this page and nothing to do with this disputed section. I understand the issues with PDFs and am trying to find already published sources on them - the problem being that KI quite rightly do not normally make public the outcome of scientific misconduct investigations. The Italian court outcome should be public somewhere but I don't speak Italian so have not yet found a reference. I will try to in the coming days. — Preceding unsigned comment added by 149.254.234.180 (talk) 16:36, 15 November 2015 (UTC)

I've marked the edit request as declined. My impression is that this case has changed considerably over the past year, and the original requester meant to come back "in the coming days" but has not for 12 months. Likely got side-tracked. Happy to reconsider fresh edit requests. Thanks! Ajpolino (talk) 21:42, 17 November 2016 (UTC)

Details in the investigation have been updated since this discussion happened. In case anyone is interested, the Karolinska Institute has a page detailing the results of the investigations and fallout available at http://ki.se/en/news/macchiarini Littlejohn657 (talk) 04:46, 8 June 2017 (UTC)

Suggested addition

Hello, I think under the 'surgeries performed' section it would be helpful to include Julia Tuulik since she was the first recipient of a synthetic trachea who was not terminally ill. This is quite an important dimension to the story. I would do it myself but I don't really know how to write it in the correct style. — Preceding unsigned comment added by 95.145.8.193 (talk) 18:19, 31 October 2016 (UTC)

Zhadyra Iglikova (Жадыра Игликова) case

7th december 2010, Zhadyra underwent surgery based on Paolo Macchiarini’s technique. Surgery was conducted by Vladimir Parshin (Владимир Паршин) under Paolo Macchiarini’s supervision in Rossiyskiy Nauchnyy Tsentr khirurgii RAMN im. B.V. Petrovskogo.

• https://mariakonovalenko.wordpress.com/2010/12/30/the-main-result-of-the-year-the-first-regenerative-medicine-surgery-in-russia/
• http://m-batin.livejournal.com/96309.html
• https://web.archive.org/web/20110316015003/http://www.scienceagainstaging.com/News/news_25.html
• https://web.archive.org/web/20111106042613/http://www.scienceagainstaging.com/Press/press_13.html — Preceding unsigned comment added by 31.170.105.231 (talk) 01:55, 23 December 2016 (UTC)

List of lies and dead patients needed

Yes, I am aware of BLP. Still, having read 10+ secondary materials, this we need to call spade a spade and list the lies (falsified data) that helped to kill patients, and how the (forced) retractions belatedly saved lives. Pride and lies before a fall.

For starters read this and the related posts, and then the RSes reffed there:

https://forbetterscience.com/2018/09/03/megagrant-the-russian-docu-novel-of-paolo-macchiarini/

-》 let us update this art with such RSes listed in this series

-》 let us list the actual patients who died due to his (their, actually) breaking the procedural rules

Zezen (talk) 00:04, 11 February 2019 (UTC)

There have been a lot of reliable sources published about the subject; which are absent in the article. Will be indulging in a major editing session, soon. ∯WBG^converse 12:42, 9 March 2019 (UTC)

Pinging Winged Blades of Godric - ta again for this promise. Will you update it, or should I?

Zezen (talk) 08:44, 27 March 2019 (UTC)

I earlier this week added this source material from Karolinska Institutet in Sweden to the article's list of sources: "https://news.ki.se/the-macchiarini-case-timeline" which is kind of a list (it's a timeline) but I am not sure if it's such a list that you ask for. Domus123 (talk) 17:05, 13 November 2023 (UTC)

Paolo macchiarini

Some of your statements are incorrect, according to ABC News - 20/20. 68.100.86.246 (talk) 02:05, 24 July 2022 (UTC)

Proposed partial restructuring

I propose moving the content in the inexplicitly titled 'Other misconduct' section to the existing sections 'Personal life' (essentially comprising his relationship with Benita Alexander) and 'In popular culture' (essentially comprising the Vanity Fair content). Comments? Jmc (talk) 20:20, 7 December 2023 (UTC)