Talk:Septic shock/Archive 1

Statistical conflict

I just thought I'd mention that the sepsis article states that the mortality rate from septic shock is >60%, while this article states it as about fifty. Neither is sourced, I believe. I'm not an expert on the subject, but I thought I'd point it out.--Vlmastra 19:05, 8 February 2007 (UTC)[reply]

Actually, to quote a single mortality rate, for adults, due to "septic shock" is a gross oversimplification. Mortality is difficult to pin down for any one individual, but relates roughly to a) APACHE II score b) Number of failing organ systems due to septic shock c) Age. WRP MD FRCPC, Critical Care Medicine

Internally inconsistent:

"To diagnose septic shock[1] the following two criteria must be met:

  "1. Refractory hypotension - hypotension despite adequate fluid resuscitation.
         * In adults it is defined as a systolic blood pressure < 90 mmHg, or a MAP < 60 mmHg, without the requirement for inotropic support, or a reduction of 40 mmHg in the systolic blood pressure from baseline.
         * In children it is BP < 2 SD of the normal blood pressure.

"In addition to the two criteria above, two or more of the following must be present:"

  Also the link to the full text of the source cited denies the existence of that part of reality.

Tazster (talk) 20:59, 14 March 2008 (UTC)[reply]

Untitled

I'm not a doctor. I just read somewhere that infusion of nitrous oxide in cases of shock works very well. A friend suffered from it and I told the doctor what I had read. Although, I believe, he did not use a nitrous oxide infusion, it triggered him to find a drug connected with it. This he used, with happy results. —Preceding unsigned comment added by 71.119.58.197 (talk) 05:16, 17 May 2009 (UTC)[reply]

This can't be the case of septic shock. In septic shock there is a drop in peripheral resistances, nitric oxide lower itself vascular peripherals resistances and may worsen the tissues hypoperfusion, so, not only this medication is not present in guidelines It is contraindicated. Traditionally endogenous nitric oxide has been related to the physiopathology of septic shock.^[1]Vixxovs (talk) 14:36, 1 August 2019 (UTC)[reply]

References

^ https://www.sciencedirect.com/science/article/pii/S0005272899000316

References

I have formatted the references uniformly. I tagged one as possibly unreliable, it was an animal study. I tagged one with page needed. I suggest some rewriting using "Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2012" as I think this is the definitive work on the subject. The references for this article could be used for detail or if preferred. - - MrBill3 (talk) 05:32, 9 May 2014 (UTC)[reply]

I still don't understand

I still don't understand about this. Give me a easiest way to understand. ProInHistory (talk) 04:34, 8 June 2016 (UTC)[reply]

IV Vitamin C and Thiamine Treatment for Sepsis

Someone might want to mention this in the article:

http://6abc.com/health/simple-inexpensive-combo-could-be-sepsis-cure/1820948/ https://emcrit.org/pulmcrit/metabolic-sepsis-resuscitation/

https://www.sciencedaily.com/releases/2010/11/101117184457.htm — Preceding unsigned comment added by 46.208.235.87 (talk) 03:13, 29 March 2017 (UTC)[reply]

These are not suitable sources and it's too early to talk about this despite it being interesting. It hasn't yet been formally studied in high-quality studies or reviewed in secondary sources per WP:MEDRS. TylerDurden8823 (talk) 03:15, 29 March 2017 (UTC)[reply]

Steroids...

Systematic review just out: doi:10.1007/s00134-018-5197-6 JFW | T@lk 13:30, 25 July 2018 (UTC)[reply]

[1] ttps://www.sciencedirect.com/science/article/pii/S0005272899000316

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