Talk:Trodusquemine

The following Wikipedia contributor has declared a personal or professional connection to the subject of this article. Relevant policies and guidelines may include conflict of interest, autobiography, and neutral point of view.
Their edits to this article were last checked for neutrality on 20 April 2024 by Whywhenwhohow. Error: Disclosures that use the |checked= parameter should also use |editedhere=yes for at least one contributor.

ZASLOFF (talk · contribs) This user has declared a connection.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Trodusquemine.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

The following Wikipedia contributors may be personally or professionally connected to the subject of this article. Relevant policies and guidelines may include conflict of interest, autobiography, and neutral point of view.

Mzasloff (talk · contribs) This user has contributed to the article.
Michael zasloff (talk · contribs) This user has contributed to the article. This user has declared a connection.
RPipiens (talk · contribs) This user has contributed to the article.
Itsashaunparty (talk · contribs) This user has contributed to the article. This user has declared a connection.
38.126.147.226 (talk · contribs) This user has contributed to the article.

The works of ZASLOFF[edit]

@ZASLOFF: Several of have noted that you've reverted the article to your referred versions 3 times over the last month. We can understand why, as you have declared yourself as an expert in the field, and have been adding references to articles that you seem to have published. Hopefully you can see that this is a conflict of interest, as will not be neutral when judging whether your own work is appropriate for inclusion. You're also adding references in a format that doesn't match the manual of style for references; bare PMIDs aren't particularly helpful, and also mask your conflict on interest. See you talk page for further discussion on conflicts of interest on your talk page.

For example, the list of references you've included isn't particularly helpful:

PMID=11360152
PMID=34698757
PMID=34698757
PMID=15688348
PMID=27516602
PMID=12086938
PMID=12086938
PMID=15336441
PMID=28899902
PMID=34794959
PMID=29302341
PMID=29302341
PMID=31915254
PMID=29953201
PMID=35958694
PMID=34794959

Klbrain (talk) 18:27, 19 April 2024 (UTC)[reply]

Here's how these would be better formatted, using the 'cite journal' template for the first 3 of these:

Zasloff, M; Williams, JI; Chen, Q; Anderson, M; Maeder, T; Holroyd, K; Jones, S; Kinney, W; Cheshire, K; McLane, M (May 2001). "A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties". International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 25 (5): 689–97. doi:10.1038/sj.ijo.0801599. PMID 11360152.
Limbocker, R; Errico, S; Barbut, D; Knowles, TPJ; Vendruscolo, M; Chiti, F; Zasloff, M (20 April 2022). "Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic". Natural product reports. 39 (4): 742–753. doi:10.1039/d1np00042j. PMID 34698757.
Limbocker, R; Errico, S; Barbut, D; Knowles, TPJ; Vendruscolo, M; Chiti, F; Zasloff, M (20 April 2022). "Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic". Natural product reports. 39 (4): 742–753. doi:10.1039/d1np00042j. PMID 34698757.

If you need a hand doing this, let us know. Klbrain (talk) 18:30, 19 April 2024 (UTC)[reply]

Thanks. I will put them into the format you suggest. I used the PMID format since it the reference can be readily accessed by Google. With respect to my writing of the piece on Trodusquemine, I am the current international expert on the class of molecules, which my lab discovered at the NIH and Penn. The references include all published reports in peer reviewed journals, without prejudice.

The prior contribution is factually incorrect and fails to communicate the science underlying this compound.

Thank you for your taking time to improve my contribution. ZASLOFF (talk) 19:28, 19 April 2024 (UTC)[reply]

@ZASLOFF: discussions on both your talk page and this article explain how your edits are considered to be a conflict of interest, provide pointers to the policies, and explain how the provided citations are not in a useful format. Please review Wikipedia:Conflicts of interest (medicine), Wikipedia:Identifying reliable sources (medicine), Wikipedia:Manual of Style/Medicine-related articles before posting again. Are you using multiple user names and/or accounts? --Whywhenwhohow (talk) 00:44, 6 May 2024 (UTC)[reply]

@ZASLOFF: It appears that your edits are self-promoting, self-referential, and likely biased. It also appears that you have previously edited the article using multiple user names and/or accounts. Please stop adding your content until you get consensus. You wrote In the case of Trodusquemine I led the discovery team and have been responsible for all early development work, and still remain involved its development. Those are all reasons why you shouldn't be directly editing the article. --Whywhenwhohow (talk) 05:41, 7 May 2024 (UTC)[reply]

As a consequence of my expertise in an area I discovered (the aminosterol family), and one with very limited activity outside of a few labs, I am routinely asked to provide guidance as well as materials. I chose not to "hide" my name in order to validate the source of the contribution. Every sentence in the Trodusquemine contribution is supported by a reference. If the compound were a commercial product I fully agree with your concerns. My contribution is meant to highlight the many excellent studies of labs around the world that have participated in research on trodusquemine, and give these groups the credit they deserve. ZASLOFF (talk) 16:47, 9 May 2024 (UTC)[reply]

I should also mention that I have only one user name. ZASLOFF (talk) 16:50, 9 May 2024 (UTC)[reply]

What I will do in response to your concerns regarding self-referral , is to remove the direct reference to myself in the contribution. In place of It was isolated from the liver of the dogfish shark by Michael Zasloff and colleagues in 2000 is will substitute It was isolated from the liver of the dogfish shark in 2000... ZASLOFF (talk) 16:56, 9 May 2024 (UTC)[reply]