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Wiki Education Foundation-supported course assignment

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 4 February 2019 and 5 May 2019. Further details are available on the course page. Student editor(s): Simssl.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 04:30, 18 January 2022 (UTC)[reply]

Wiki Education Foundation-supported course assignment

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 8 July 2019 and 3 August 2019. Further details are available on the course page. Student editor(s): Cryptogirl757. Peer reviewers: DrCupino.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 04:30, 18 January 2022 (UTC)[reply]

Review

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I've found an extremely comprehensive review of the literature here , with 130 citations :

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The link is also apparent from another wiki page on memantine : "Memantine is used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors. It was first synthesized by Eli Lilly and Company in 1968 as a potential agent to treat diabetes; the NMDA activity was discovered in the 1980s."

Darwinerasmus (talk) 10:17, 24 February 2019 (UTC)[reply]

References

Peer Review for Type 3 Diabetes (28 July 2019)

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The redirect for "Not to be confused with" at the beginning is excellent. The lead starts out clearly. Saying that this diagnosis is not embraced by the the medical community is important, though a reference supporting this would give it more weight. Are Neurofibrillary tangles made up of hyperphorphorylated tau proteins or are they separate? The "and" makes it seem like they are distinct from one another. If possible, it might be helpful to add more Wikipedia links for terms like "neurofibrillary tangles" and "hypephosphorylated tau" so that information can be accessed more quickly.

It could be helpful to add a brief bit on what GSK-3beta does in the brain. The Ramesk reference[1] you cited mentions that GSK-3beta directly binds Tau protein to microtubles, so it may be possible to expand the sentence "Glycogen synthase kinase 3β (GSK-3β) plays a key role in the formation of the neurofibrillary tangles." into 2-3 sentences showing how they interact.

Overall, this is a great start to an entry on a topic that is just beginning to be discussed but is not commonly known in medicine.

Thank you so much for the feed back! I love the idea of adding the links to tau proteins and neurofibrillary tangles I am going to implement that immediately. Cryptogirl757 (talk) 00:26, 31 July 2019 (UTC)[reply]

References

  1. ^ "Is Alzheimer's disease a Type 3 Diabetes? A Critical Appraisal".

Project Medicine: Article Under Review My Medical School

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Dear Editors,

This article is currently under review with further edits to be made by Doctor of Medicine students from the University of Notre Dame as part of the Wikipedia Project Medicine in an effort to improve the page quality and content. Edits shall be complete within the next fortnight. We kindly ask for your patience during this process.

Thank you. — Preceding unsigned comment added by Missfirefly (talkcontribs) 19:40, 25 January 2020 (UTC)[reply]

Close paraphrasing

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Some of the phrasing in this article was quite odd which normally indicates the content is copied and words changed using thesaurus, and so is the content. "Melatonin is discharged" = PMC5539639 paragraph 2, some words changed. The entire treatment section is paraphrasing of this article PMC5501038, which is an opinion piece, not indicative of the content.

The sources do not line up with the text.

I note that this is part of an educational assignment so I am pinging the instructors and student.

User:MimiGregg Carrolquadrio User:Zmrob25

Additionally it would be great if the referencing section can be fixed, mistakenly the University's proxy links rather than dois or PMIDs have been linked, this is hard to fix. — Preceding unsigned comment added by PainProf (talkcontribs) 20:06, 20 June 2020 (UTC)[reply]

Now, there are no more usyd links and the "Melatonin is discharged" part is only two sentences, so I'll remove the tag. Aaron Liu (talk) 22:38, 19 November 2023 (UTC)[reply]

POV fork

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Seems from the sources T3D is just another name for Alzheimer's disease, albeit with a different proposed cause. That being the case, shouldn't this article be blanked and redirected to Alzheimer's disease, where a few sentences can outline what T3D is proposed to be? Bon courage (talk) 12:11, 11 December 2022 (UTC)[reply]

Merger discussion

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The following discussion is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.


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Agreed. I'd like to propose that this article be merged with the main Alzheimer's disease article. ChiaLynn (talk) 19:12, 29 May 2023 (UTC)[reply]

The discussion above is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.