Template:2005 NL Central standings
| Team | W | L | Pct. | GB | Home | Road |
|---|---|---|---|---|---|---|
| St. Louis Cardinals | 100 | 62 | .617 | — | 50–31 | 50–31 |
| Houston Astros | 89 | 73 | .549 | 11 | 53–28 | 36–45 |
| Milwaukee Brewers | 81 | 81 | .500 | 19 | 46–35 | 35–46 |
| Chicago Cubs | 79 | 83 | .488 | 21 | 38–43 | 41–40 |
| Cincinnati Reds | 73 | 89 | .451 | 27 | 42–39 | 31–50 |
| Pittsburgh Pirates | 67 | 95 | .414 | 33 | 34–47 | 33–48 |