Template:Did you know nominations/P50 (neuroscience)

The following is an archived discussion of the DYK nomination of the article below. Please do not modify this page. Subsequent comments should be made on the appropriate discussion page (such as this nomination's talk page, the article's talk page or Wikipedia talk:Did you know), unless there is consensus to re-open the discussion at this page. No further edits should be made to this page.

The result was: promoted by Allen3 ^talk 09:35, 25 April 2014 (UTC)

P50 (neuroscience)

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... that abnormal P50 suppression is an endophenotype for schizophrenia?

Reviewed: Sofia Simmonds

Created by Staticshakedown (talk). Self nominated at 14:54, 30 March 2014 (UTC).

Article is new and big enough. Citations throughout. Listed user did the work. QPQ OK. However some writing is too jargony and I did not understand it. Terms like proband and endophenotype are not needed or need a clear explanation. So this applies to the hook, and people reading the hook will have no idea what it is talking about. It's fair enough to leave P50 as the mystery, but the rest of the hook should be comprehensible. So I suggest another hook. Perhaps use the term biological marker, it does not seem to be related to genetics. The reference provided does not confirm that P50 is an indication of schizophrenia, but that P300 is. The reference says that P50 is an ERP. And that ERPs have been used in the drug development. Perhaps there is another reference that makes a more clear statement. Graeme Bartlett (talk) 12:02, 10 April 2014 (UTC)

ALT1: ... that abnormal P50 suppression is a biomarker for schizophrenia?
All right, we can use "biological marker" if that's a more well-known term. I added another citation talking about P50 in particular as well. static shakedown ʕ •ᴥ•ʔ 16:09, 15 April 2014 (UTC)

Hook ALT1 can be understood, short enough, and the new citation confirms it. Good to go Graeme Bartlett (talk) 23:39, 24 April 2014 (UTC)