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Template:Did you know nominations/Tmem106a

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The following discussion is an archived discussion of the DYK nomination of the article below. Please do not modify this page. Subsequent comments should be made on the appropriate discussion page (such as this nomination's talk page, the article's talk page or Wikipedia talk:Did you know), unless there is consensus to re-open the discussion at this page. No further edits should be made to this page.

The result was: promoted by Carabinieri (talk) 14:16, 27 May 2012 (UTC)

Tmem106a, human, transmembrane protein[edit]

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Created/expanded by Beckx282 (talk). Nominated by Hghyux (talk) at 22:23, 14 May 2012 (UTC)

Note: I've removed Transmembrane protein and Human from the templates and whatnot, as neither is close to being eligible for DYK. MANdARAX • XAЯAbИAM 00:38, 15 May 2012 (UTC)
  • Comment I find the current hook a little flat, it seems self-evident to a reader familiar with genetics, and possibly not interesting to a general reader. I propose the following alternate hook:
Alt1: ... that the first 140 amino acids of the gene TMEM106A are deleted along with BRCA1 during early-onset breast cancer? 109.77.157.22 (talk) 14:30, 15 May 2012 (UTC)
  • Comment A gene doesn't have amino acids (it codes for them), and gene names should be italicized–these should be fixed in the article (protein names are not italicized). Because of this lack of clarity with formatting, however, it's not quite clear from the article whether the gene (TMEM106A) or the protein (TMEM106A) is being truncated. Sasata (talk) 15:12, 15 May 2012 (UTC)
  • Yes, that jarred with me too, I thought of replacing amino acids with codons or 420 bases, but that's not what it said in the article. 93.107.150.86 (talk) 18:55, 15 May 2012 (UTC)
  • Just to clarify, I just read the source for Alt1, it talks about deletions in the gene, and uses the italicized format. It doesn't mention the size of the deletion in the text, but I presume it could be read from one of the diagrams (I can't make much sense of them myself). The scale of the diagram is in kilobases, so I presume the author converted that into a number of amino acids. 93.107.150.86 (talk) 19:28, 15 May 2012 (UTC)
  • I quite like that string. It might interest more people that my original hook. Hghyux (talk to me)(talk to others) 20:13, 15 May 2012 (UTC)
  • Full review still needed now that hook discussion seems to have ended. BlueMoonset (talk) 19:16, 26 May 2012 (UTC)
    • Review completed. Hook citation, length and newness all check out. References impeccable. I did some minor formatting to clarify protein vs. gene, I notice many other articles are similarly ambiguous. Does Alt2 make it clearer? otherwise think article good to go. -- Ultracobalt  (talk) 00:54, 27 May 2012 (UTC)
Alt2: ... that the first 140 amino acids encoded by the gene TMEM106A are deleted along with BRCA1 during early-onset breast cancer?
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