Jump to content

Tripdiolide

From Wikipedia, the free encyclopedia
Tripdiolide
Names
Preferred IUPAC name
(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS,10S)-6,10-Dihydroxy-8b-methyl-6a-(propan-2-yl)-3b,4,4a,5a,6,6a,7a,7b,8a,8b,9,10-dodecahydrotris(oxireno)[2′,3′:4b,5;2′′,3′′:6,7;2′′′,3′′′:8a,9]phenanthro[1,2-c]furan-1(3H)-one
Other names
Triptodiolide
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
KEGG
UNII
  • InChI=1S/C20H24O7/c1-7(2)18-13(26-18)14-20(27-14)17(3)5-10(21)12-8(6-24-15(12)22)9(17)4-11-19(20,25-11)16(18)23/h7,9-11,13-14,16,21,23H,4-6H2,1-3H3/t9-,10-,11-,13-,14-,16+,17-,18-,19+,20+/m0/s1
    Key: PUJWFVBVNFXCHZ-SQEQANQOSA-N
  • CC(C)[C@@]12[C@@H](O1)[C@H]3[C@@]4(O3)[C@]5(C[C@@H](C6=C([C@@H]5C[C@H]7[C@]4([C@@H]2O)O7)COC6=O)O)C
Properties
C20H24O7
Molar mass 376.405 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Tripdiolide is an anti-inflammatory isolate of Tripterygium wilfordii.[1]

References

[edit]
  1. ^ Ma, J; Dey, M; Yang, H; Poulev, A; Pouleva, R; Dorn, R; Lipsky, PE; Kennelly, EJ; Raskin, I (2007). "Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii". Phytochemistry. 68 (8): 1172–8. Bibcode:2007PChem..68.1172M. doi:10.1016/j.phytochem.2007.02.021. PMID 17399748.