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UNC5A

From Wikipedia, the free encyclopedia
UNC5A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesUNC5A, UNC5H1, unc-5 netrin receptor A
External IDsOMIM: 607869; MGI: 894682; HomoloGene: 41474; GeneCards: UNC5A; OMA:UNC5A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_133369

NM_153131
NM_001311128

RefSeq (protein)

NP_588610

NP_001298057
NP_694771

Location (UCSC)Chr 5: 176.81 – 176.88 MbChr 13: 55.1 – 55.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Netrin receptor UNC5A is a protein that in humans is encoded by the UNC5A gene.[5]

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM][5]

Interactions

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UNC5A has been shown to interact with MAGED1.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113763Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025876Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: UNC5A unc-5 homolog A (C. elegans)".
  6. ^ Williams ME, Strickland P, Watanabe K, Hinck L (May 2003). "UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE". The Journal of Biological Chemistry. 278 (19): 17483–90. doi:10.1074/jbc.M300415200. PMID 12598531.

Further reading

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