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Professor
Thomas Alexander Owen-Hughes
PhD FRSE
EducationUniversity of Oxford University of Edinburgh
Organization(s)University of Dundee


Director of Wellcome Trust Centre for Gene Regulation and Expression
Notes
Scopus ID: 7003683341


ORCiD: https://orcid.org/0000-0002-0618-8185


Tom Owen-Hughes

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Career and Education

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Professor Tom Owen-Hughes completed his bachelor's degree in Molecular Biology at the University of Edinburgh from 1984 to 1988. He then went on to complete his PhD in Biochemistry at the University of Oxford from 1989 to 1993 [1].

In 1998, Prof. Tom Owen-Hughes was recruited to Dundee from The Pennsylvania State University where he had worked as a postdoctoral research fellow with Professor Jerry Workman [2]. During his time at the University of Dundee, he became a Wellcome Trust Senior Research Fellow and was appointed as the Director of the Centre for Gene Regulation and Expression.

He was also a contributor to the Science Saturdays: Guardians of Genome project in 2018 - a VR game about repairing damaged DNA aimed at all ages, which was awarded the Brian Cox Prize for Public Engagement Project of the year [4].



Research

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Prof. Tom Owen-Hughes’ research at the Centre for Gene Regulation and Expression is centred around chromatin structure and function [2]. His research group has investigated the functions of ATP dependent remodelling enzymes and their interplay with the modification of histones and histone chaperones to regulate gene expression [2]. The experimental approaches used include biochemistry, biophysics, structural biology and functional genomics. Prof. Tom Owen-Hughes has an extensive publication list centred around the techniques mentioned above [2].


Awards and Achievements:

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  • 2000: EMBO Young Investigator - for mechanisms for ATP-dependent chromatin remodelling [9].
  • 2002: The Colworth Medal of the British Biochemical Society [8].
  • 2007: Wellcome Trust Senior Research Fellowship [2].
  • 2007: Member of the European Molecular Biology Organisation [7].
  • 2009: Fellow of the Royal Society of Edinburgh [6].
  • 2012: Wellcome Trust Senior Research Fellowship [5].
  • 2018: Owen-Hughes becomes the Dundee representative of the SCMI (Scottish Centre for Macromolecular Imaging) management committee [10].
  • Executive Member of SULSA (Scottish Universities Life Science Alliance - an association of 11 Scottish Universities with the aim to advance life science research) [11].


References

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  1. Owen-Hughes T. Tom Owen-Hughes [Internet]. LinkedIn. 2020 [cited 3 August 2020]. Available from: https://www.linkedin.com/in/tom-owen-hughes-2b6ba9170/?originalSubdomain=uk
  2. Professor Tom Owen-Hughes FRSE [Internet]. School of Life Sciences. 2020 [cited 3 August 2020]. Available from: https://www.lifesci.dundee.ac.uk/people/tom-owen-hughes
  3. Wellcome Trust Centre for Gene Regulation and Expression [Internet]. En.wikipedia.org. 2020 [cited 3 August 2020]. Available from: https://en.wikipedia.org/wiki/Wellcome_Trust_Centre_for_Gene_Regulation_and_Expression
  4. Science Saturdays: Guardians of the Genome [Internet]. Discovery - the University of Dundee Research Portal. 2020 [cited 3 August 2020]. Available from: https://discovery.dundee.ac.uk/en/activities/science-saturdays-guardians-of-the-genome
  5. Mechanisms for remodelling chromatin | Wellcome [Internet]. Wellcome.ac.uk. 2020 [cited 3 August 2020]. Available from: https://wellcome.ac.uk/grant-funding/people-and-projects/grants-awarded/mechanisms-remodelling-chromatin
  6. RSE Honour for four Dundee professors [Internet]. School of Life Sciences. 2020 [cited 3 August 2020]. Available from: https://www.lifesci.dundee.ac.uk/news/2013/aug/20/rse-honour-four-dundee-professors
  7. Find a Member [Internet]. EMBO. 2020 [cited 3 August 2020]. Available from: https://www.embo.org/members/find-a-member.html
  8. The Colworth Medal - Biochemistry [Internet]. Biochemistry. 2020 [cited 3 August 2020]. Available from: https://www.biochemistry.org/grants-and-awards/awards/the-colworth-medal/
  9. Find an EMBO Young Investigator / EMBO Installation Grantee / EMBO Global Investigator [Internet]. Yip-search.embo.org. 2020 [cited 3 August 2020]. Available from: https://yip-search.embo.org/#/yip/2245
  10. University of Glasgow - Research Institutes - Institute of Infection, Immunity & Inflammation - MRC-University of Glasgow Centre for Virus Research - Scottish Centre for Macromolecular Imaging - About - Staff [Internet]. Gla.ac.uk. 2020 [cited 3 August 2020]. Available from: https://www.gla.ac.uk/researchinstitutes/iii/cvr/scmi/about/staff/
  11. Our Committee | SULSA [Internet]. Sulsa.ac.uk. 2020 [cited 3 August 2020]. Available from: https://www.sulsa.ac.uk/our-people/