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The basal electrical rhythm, also called the basic electrical rhythm, is the spontaneous depolarization and repolarization of pacemaker cells in the smooth muscle of the stomach, small intestine, and large intestine. This electrical rhythm is spread through gap junctions in the smooth muscle of the GI tract. These pacemaker cells, also called the interstitial cells of Cajall, control the frequency of contractions in the gastrointestinal tract. The cells can be located in either the circular or longitudinal layer of the smooth muscle in the GI tract; circular for the small and large intestine, longitudinal for the stomach. The frequency of contraction differs at each location in the GI tract beginning with three per minute in the stomach, then 12 per minute in the duodenum, 9 per minute in the ileum, and a normally low one contraction per 30 minutes in the large intestines that increases 3 to 4 times a day due to a phenomenon called mass movement. The basal electrical rhythm controls the frequency of contraction but additional neuronal and hormonal controls regulate the strength of each contraction.

Takaki, Miyako. "Gut Pacemaker Cells: The Interstitial Cells of Cajal (ICC)." Journal of Smooth Muscle Research 39.5 (2003): 137-61.

Ju, Yue-Kun, Elizabeth A. Woodcock, David G. Allen, and Mark B. Cannell. "Inositol 1,4,5-trisphosphate Receptors and Pacemaker Rhythms." Journal of Molecular and Cellular Cardiology 53.3 (2012): 375-81.

Salminen, S., C. Bouley, M.C. Boutron-Ruault, J.H. Cummings, A. Franck, G.R. Gibson, E. Isolauri, M.C. Moreau, M. Roberfroid, and I. Rowland. "Functional Food Science and Gastrointestinal Physiology and Function." British Journal of Nutrition 80 (1998): 147-71.

Wood, Jackie D. (2009), "Gastrointestinal Physiology", in Rhoades, Rodney A.; Bell, David R., Medical Physiology: Principles for Clinical Medicine (3 ed.), Philadelphia, PA: Lippincott Williams & Wilkins, pp. 463–496.

Widmaier, Eric P., Hershel Raff, and Kevin T. Strang. Vander's Human Physiology: The Mechanisms of Body Function. New York, NY: McGraw-Hill Education, 2016.

Wu T, Rayner C, Young R, Horowitz M. Gut motility and enteroendocrine secretion. Current Opinion In Pharmacology [serial online]. December 1, 2013;13(Gastrointestinal * Endocrine and metabolic diseases):928-934. Available from: ScienceDirect, Ipswich, MA. Accessed March 29, 2017.