User:Benjah-bmm27/degree/3/WHB

Self-assembly in molecular systems

• Self-assembly
• Intermolecular forces
  • Coulombic interactions / electrostatics / charge–charge interactions
  • van der Waals forces – summarised by the Hamaker constant
    • charge-dipole
    • dipole–dipole (Keesom interactions)
    • charge –non-polar (induced dipole)
    • dipole –non-polar (induced dipole / Debye interaction)
    • non-polar (instantaneous dipole / London dispersion forces)
    • magnitude of induced dipoles depend on polarizability
• Hydrophobic effect
• Phospholipid
• Self-assembled monolayers
• Surfactants
• Micelle
  • Aggregation number
  • Critical micelle concentration (monomers → micelles phase transition)
  • Other phase transitions:

→ cylinders

→ flexible bilayers / vesicles / liposomes

→ sheets (lamellar phases / planar bilayers)

→ inverted cylinders

→ inverted micelles

• Lipid bilayer
• Interaction free energy
• Thermodynamic spontaneity
• Amphiphilic molecules