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User:Chingla/Intention Tremors

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We're planning on studying the causes, symptoms, treatments, history, and research involving intention tremors in humans.

Intention tremor is a tremor upon voluntary movement. It typically occurs towards the end of a purposeful movement. It is believed to be caused by damage to the cerebellum. The cerebellum controls fine motor movements, making slight corrections to the movements produced by the motor cortex from the frontal lobe. It is believed that the problems arise from the feedback mechanisms between the cerebellum and motor cortex. The tremor is due to issues of proprioception. The severity of the tremors is variant and the presentation can also be variant in patients.

Diagnosis of these tremors can be determined by symptoms, as well as cerebellar degeneration seen in an MRI. Intention tremors are commonly seen due to trauma, Multiple Sclerosis, Wilson's Disease, Alcoholism, substance abuse, and stroke.

Although there are some techniques that have a slight effect on the tremors, no cure has been found to date. Some techniques used to alleviate the tremors produced include modern medicine, such as propranolol, primidone, glutethimide, carbamazepine, isoniazid, clonazepam, buspirone and topiramate, as well as surgical options, such as contingent deep brain stimulation.

We will form the page through the collective effort of the group, distributing the work evenly between our members, by meeting several times during the semester to discuss the page, research and add to the article.

References,

Seeberger, Lauren C. "Cerebellar Tremor - Definition and Treatment." 2005. Colorado Neurological Institute.

Flament, D, Villus, T, Hore, J. "Dependence of Cerebellar Tremor on Proprioceptive but Not Visual Feedback." 1984. Experimental Neurology.

Brice, J, Mclellan, L. "Suppression of Intention Tremor By Contingent Deep-Brain Stimulation."1980. Lancet.