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User:Hadoooookin/to do list/pharmaceutical

From Wikipedia, the free encyclopedia

DRUG DESIGN (Parker) The molecular mechanisms by which drugs act in the body. What is drug formulation? Process of:

  • devising
  • preparing
  • developing
  • manufacturing
  • producing the end product

Type of product:

  • capsule
  • tablet
  • cream


Drug profile:

  • Origin
  • Chemistry
  • Action / pharmacology
  • Uses
  • Preparation

Module Descriptor: brief description of module Integrated module: issues

  • Drug discovery
  • Drug design
  • Drug development
  • Drug action: chemical aspects
  • The consequences of product formulation on the effectiveness of drugs

Module descriptors: Aims

  • Chemical basis of drug-receptor interactions
  • Approaches to rational drug design and development
  • relate chemical structure and associated physicochemical properties to stability, ADME
  • relate drug molecule chemistry to the formulation, uniformity, bioavailability, and stability of pharmaceutical products
  • preformulation requirements of new drug entities
  • formulation requirements
  • quality assurance
  • GMP
  • natural products

Module descriptor: learning outcomes

  • Drug target interactions principles
  • Bonding
  • Complementarity
  • Optical and geometric specificity of isomers
  • Rational drug design and development
  • Structural aspects of
    • Drug-enzyme interactions
    • Drug-receptor interactions
  • Drug development by structural modification
  • Biopharmaceutics wrt the physciochemical parameters of drugs
  • Drug metabolism and transfer
  • Metabolic processes that occur at sites on drug molecules
  • Possible metabolites produced
  • Effect of processes on drug activity