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Georg Jander
Jander giving a lecture on cardiac glycoside evolution in plants
Born1965
Königstein im Taunus, Germany
NationalityAmerican
Alma materWashington University, Harvard University
SpouseLucia Jander
Children4
Scientific career
Fieldsplant biology, entomology, chemical ecology
InstitutionsBoyce Thompson Institute, Cornell University
Thesis Genetic studies on protein folding and protein secretion in Escherichia coli  (1995)
Doctoral advisorJon Beckwith
Other academic advisorsFrederick M. Ausubel
Doctoral studentsTengfang Huang, Dezi Elzinga, John Ramsey, Yann-Ru Lou, Shaoqun Zhou
Websitelab website

Georg Jander is an American plant biologist at the Boyce Thompson Institute in Ithaca, New York.[1] He has an adjunct appointment in the Plant Biology Section of the School of Integrative Plant Sciences at Cornell University.[2] Jander is known for his molecular research identifying genes for biochemical compounds of ecological and agricultural importance, particularly those plant traits involved in resistance to insect pests.[3][4]

Education[edit]

Jander received and undergraduate degree in Computer Science from Washington University in 1983.[5] As a PhD student in Microbiology and Molecular Genetics, working under the supervision of Jon Beckwith at Harvard Medical School, he wrote a thesis titled Genetic studies on protein folding and protein secretion in Escherichia coli, and is an author of journal publications in this research area.[3][6][7][8][9][10] While working as a postdoctoral fellow in the lab of Fred Ausubel at Massachusetts General Hospital, Jander initiated research on the molecular biology and genetics of Arabidopsis thaliana defense against insect herbivores.[11][12][13][14] He continued his research training in plant genetics and molecular biology as a scientist at the Monsanto Company from 1998-2002.[15][16][17][18][19][20]

Research[edit]

Since joining the Boyce Thompson Institute as a faculty member in 2002, Jander has studied several plant species, including maize (Zea mays),[21][22][23][24] mouse-ear cress (Arabidopsis),[25][26][27] wallflowers in the genus Erysimum,[28][29][30] and milkweeds in the genus Asclepias.[31] In each plant species, Jander's laboratory uses techniques in biochemical genetics to identify the genetic causes of plant secondary metabolism involved in plant defenses against insects. A particular focus of the Jander lab has been research involving plant interactions with aphids.[32][33][34][35][36][37][38][39][40] Jander's research publications have been cited more than 17,000 times by other scientists.[3]

Jander's research collaborators and co-authors in the field of chemical ecology include: Anurag Agrawal, Clare Casteel, Andre Kessler, Gaurav Moghe, Katja Poveda, Rob Raguso, and Jennifer Thaler at Cornell University, Eric Schmelz at UC San Diego, Melkamu Woldemariam at The College of New Jersey, Cynthia Holland at Williams College, Asaph Aharoni at the Weizmann Institute, and Tobias Züst at the University of Zurich.[3]

Graduate student alumni of the Jander lab are: Tengfang Huang, VP for Research at Elo Life Sytems,[41] Dezi Elzinga, research scientist at Zymtronix,[42][43] John Ramsey, research molecular biologist at the USDA,[44] Yann-Ru Lou, assistant professor in Plant Biology at UC Davis,[45] and Shaoqun (Simon) Zhou, principal investigator at the Agricultural Genomics Institute of Shenzhen.[46]

Since 2005, Jander has been the principal investigator for a plant-focused undergraduate summer internship program at the Boyce Thompson Institute.[47] Undergraduate research internships are currently funded by US National Science Foundation award #1850796 and United States Department of Agriculture award #2022-67037-3622.[48][49] Notable alumni of the summer research program include Adam Steinbrenner, assistant professor at the University of Washington,[50] Kaitlin Gold, assistant professor at Cornell University,[51] and Karl Kremling, senior scientist at Inari Agriculture.[52][53]

Honors and Awards[edit]

Friedrich Wilhelm Bessel Research Award from the Humboldt Foundation (2011)[54]

Fellow, American Association for the Advancement of Science (AAAS) (2012)[55]

Fellow, American Society of Plant Biologists (ASPB) (2022)[56]

References[edit]

  1. ^ "Welcome to Boyce Thompson Institute - Inspired by how plants work for humanity". Boyce Thompson Institute. Retrieved 2022-12-24.
  2. ^ "Georg Jander". CALS. Retrieved 2022-12-24.
  3. ^ a b c d "Georg Jander". scholar.google.com. Retrieved 2022-12-24.
  4. ^ "Georg Jander". Boyce Thompson Institute. Retrieved 2022-12-24.
  5. ^ "Alumni and Friends - Washington University in St. Louis". Alumni and Friends. Retrieved 2022-12-24.
  6. ^ Jander, G; Cronan, J E; Beckwith, J (1996). "Biotinylation in vivo as a sensitive indicator of protein secretion and membrane protein insertion". Journal of Bacteriology. 178 (11): 3049–3058. doi:10.1128/jb.178.11.3049-3058.1996. ISSN 0021-9193. PMC 178051. PMID 8655479.{{cite journal}}: CS1 maint: PMC format (link)
  7. ^ Guilhot, C; Jander, G; Martin, N L; Beckwith, J (1995-10-10). "Evidence that the pathway of disulfide bond formation in Escherichia coli involves interactions between the cysteines of DsbB and DsbA". Proceedings of the National Academy of Sciences. 92 (21): 9895–9899. doi:10.1073/pnas.92.21.9895. ISSN 0027-8424. PMC 40909. PMID 7568240.{{cite journal}}: CS1 maint: PMC format (link)
  8. ^ Jander, G.; Martin, N.L.; Beckwith, J. (1994). "Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation". The EMBO Journal. 13 (21): 5121–5127. doi:10.1002/j.1460-2075.1994.tb06841.x. PMC 395459. PMID 7957076.{{cite journal}}: CS1 maint: PMC format (link)
  9. ^ Jander, G.; Martin, N.L.; Beckwith, J. (1994). "Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation". The EMBO Journal. 13 (21): 5121–5127. doi:10.1002/j.1460-2075.1994.tb06841.x. ISSN 0261-4189. PMC 395459. PMID 7957076.{{cite journal}}: CS1 maint: PMC format (link)
  10. ^ Braun, V; Neuss, B; Ruan, Y; Schiebel, E; Schöffler, H; Jander, G (1987). "Identification of the Serratia marcescens hemolysin determinant by cloning into Escherichia coli". Journal of Bacteriology. 169 (5): 2113–2120. doi:10.1128/jb.169.5.2113-2120.1987. ISSN 0021-9193. PMC 212107. PMID 2437098.{{cite journal}}: CS1 maint: PMC format (link)
  11. ^ Jander, Georg; Cui, Jianping; Nhan, Betty; Pierce, Naomi E.; Ausubel, Frederick M. (2001-06-01). "The TASTY Locus on Chromosome 1 of Arabidopsis Affects Feeding of the Insect Herbivore Trichoplusia ni". Plant Physiology. 126 (2): 890–898. doi:10.1104/pp.126.2.890. ISSN 1532-2548. PMC 111178. PMID 11402216.{{cite journal}}: CS1 maint: PMC format (link)
  12. ^ Cui, Jianping; Jander, Georg; Racki, Lisa R.; Kim, Paul D.; Pierce, Naomi E.; Ausubel, Frederick M. (2002-06-01). "Signals Involved in Arabidopsis Resistance to Trichoplusia ni Caterpillars Induced by Virulent and Avirulent Strains of the Phytopathogen Pseudomonas syringae". Plant Physiology. 129 (2): 551–564. doi:10.1104/pp.010815. ISSN 1532-2548. PMC 161673. PMID 12068100.{{cite journal}}: CS1 maint: PMC format (link)
  13. ^ Bush, Jenifer; Jander, Georg; Ausubel, Frederick M. (2006-03-15), "Prevention and Control of Pests and Diseases", Arabidopsis Protocols, vol. 323, New Jersey: Humana Press, pp. 13–26, doi:10.1385/1-59745-003-0:13, ISBN 978-1-59745-003-4, retrieved 2022-12-24
  14. ^ Clay, Nicole K.; Adio, Adewale M.; Denoux, Carine; Jander, Georg; Ausubel, Frederick M. (2009-01-02). "Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response". Science. 323 (5910): 95–101. doi:10.1126/science.1164627. ISSN 0036-8075. PMC 2630859. PMID 19095898.{{cite journal}}: CS1 maint: PMC format (link)
  15. ^ Jander, Georg; Baerson, Scott R.; Hudak, Jebecka A.; Gonzalez, Kathleen A.; Gruys, Kenneth J.; Last, Robert L. (2003-01-01). "Ethylmethanesulfonate Saturation Mutagenesis in Arabidopsis to Determine Frequency of Herbicide Resistance". Plant Physiology. 131 (1): 139–146. doi:10.1104/pp.102.010397. ISSN 0032-0889. PMC 166794. PMID 12529522.{{cite journal}}: CS1 maint: PMC format (link)
  16. ^ Jander, Georg; Norris, Susan R.; Rounsley, Steven D.; Bush, David F.; Levin, Irena M.; Last, Robert L. (2002-06-01). "Arabidopsis Map-Based Cloning in the Post-Genome Era". Plant Physiology. 129 (2): 440–450. doi:10.1104/pp.003533. ISSN 1532-2548. PMC 1540230. PMID 12068090.{{cite journal}}: CS1 maint: PMC format (link)
  17. ^ Jander, Georg; Norris, Susan R.; Joshi, Vijay; Fraga, Michele; Rugg, Arthur; Yu, Shaoxia; Li, Lily; Last, Robert L. (2004). "Application of a high-throughput HPLC-MS/MS assay to Arabidopsis mutant screening; evidence that threonine aldolase plays a role in seed nutritional quality". The Plant Journal. 39 (3): 465–475. doi:10.1111/j.1365-313X.2004.02140.x.
  18. ^ Kim, Jae Hak; Durrett, Timothy P.; Last, Robert L.; Jander, Georg (2004). "Characterization of the Arabidopsis TU8 Glucosinolate Mutation,an Allele of TERMINAL FLOWER2". Plant Molecular Biology. 54 (5): 671–682. doi:10.1023/B:PLAN.0000040897.49151.98. ISSN 0167-4412.
  19. ^ Kliebenstein, Daniel J.; D’Auria, John C.; Behere, Aditi S.; Kim, Jae Hak; Gunderson, Kevin L.; Breen, John N.; Lee, Grace; Gershenzon, Jonathan; Last, Robert L.; Jander, Georg (2007-08-07). "Characterization of seed-specific benzoyloxyglucosinolate mutations in Arabidopsis thaliana: Benzoyloxyglucosinolates in Arabidopsis". The Plant Journal. 51 (6): 1062–1076. doi:10.1111/j.1365-313X.2007.03205.x.
  20. ^ Lee, Minsang; Huang, Tengfang; Toro-Ramos, Tatiana; Fraga, Michele; Last, Robert L.; Jander, Georg (2008). "Reduced activity of Arabidopsis thaliana HMT2, a methionine biosynthetic enzyme, increases seed methionine content". The Plant Journal. 54 (2): 310–320. doi:10.1111/j.1365-313X.2008.03419.x. ISSN 0960-7412.
  21. ^ Richter, Annett; Powell, Adrian F.; Mirzaei, Mahdieh; Wang, Lucy J.; Movahed, Navid; Miller, Julia K.; Piñeros, Miguel A.; Jander, Georg (2021). "Indole‐3‐glycerolphosphate synthase, a branchpoint for the biosynthesis of tryptophan, indole, and benzoxazinoids in maize". The Plant Journal. 106 (1): 245–257. doi:10.1111/tpj.15163. ISSN 0960-7412.
  22. ^ Zhou, Shaoqun; Bae, Justin S.; Bergstrom, Gary C.; Jander, Georg (2018). "Fusarium graminearum‐ induced shoot elongation and root reduction in maize seedlings correlate with later seedling blight severity". Plant Direct. 2 (7). doi:10.1002/pld3.75. ISSN 2475-4455. PMC 6508817. PMID 31245738.{{cite journal}}: CS1 maint: PMC format (link)
  23. ^ Zhou, Shaoqun; Kremling, Karl A.; Bandillo, Nonoy; Richter, Annett; Zhang, Ying K.; Ahern, Kevin R.; Artyukhin, Alexander B.; Hui, Joshua X.; Younkin, Gordon C.; Schroeder, Frank C.; Buckler, Edward S.; Jander, Georg (2019). "Metabolome-Scale Genome-Wide Association Studies Reveal Chemical Diversity and Genetic Control of Maize Specialized Metabolites". The Plant Cell. 31 (5): 937–955. doi:10.1105/tpc.18.00772. ISSN 1040-4651. PMC 6533025. PMID 30923231.{{cite journal}}: CS1 maint: PMC format (link)
  24. ^ Zhou, Shaoqun; Zhang, Ying K.; Kremling, Karl A.; Ding, Yezhang; Bennett, John S.; Bae, Justin S.; Kim, Dean K.; Ackerman, Hayley H.; Kolomiets, Michael V.; Schmelz, Eric A.; Schroeder, Frank C.; Buckler, Edward S.; Jander, Georg (2019). "Ethylene signaling regulates natural variation in the abundance of antifungal acetylated diferuloylsucroses and Fusarium graminearum resistance in maize seedling roots". New Phytologist. 221 (4): 2096–2111. doi:10.1111/nph.15520. ISSN 0028-646X.
  25. ^ Lou, Yann‐Ru; Ahmed, Sheaza; Yan, Jian; Adio, Adewale M.; Powell, Hannah M.; Morris, Paul F.; Jander, Georg (2020). "Arabidopsis ADC1 functions as an N δ ‐acetylornithine decarboxylase". Journal of Integrative Plant Biology. 62 (5): 601–613. doi:10.1111/jipb.12821. ISSN 1672-9072.
  26. ^ Huang, Tengfang; Jander, Georg (2017). "Abscisic acid-regulated protein degradation causes osmotic stress-induced accumulation of branched-chain amino acids in Arabidopsis thaliana". Planta. 246 (4): 737–747. doi:10.1007/s00425-017-2727-3. ISSN 0032-0935.
  27. ^ Lou, Yann-Ru; Bor, Melike; Yan, Jian; Preuss, Aileen S; Jander, Georg (2016). "Arabidopsis NATA1 acetylates putrescine and decreases defense-related hydrogen peroxide accumulation". Plant Physiology. 171: 1443–1455. doi:10.1104/pp.16.00446. ISSN 0032-0889. PMC 4902623. PMID 27208290.{{cite journal}}: CS1 maint: PMC format (link)
  28. ^ Züst, Tobias; Strickler, Susan R; Powell, Adrian F; Mabry, Makenzie E; An, Hong; Mirzaei, Mahdieh; York, Thomas; Holland, Cynthia K; Kumar, Pavan; Erb, Matthias; Petschenka, Georg; Gómez, José-María; Perfectti, Francisco; Müller, Caroline; Pires, J Chris (2020-04-07). "Independent evolution of ancestral and novel defenses in a genus of toxic plants (Erysimum, Brassicaceae)". eLife. 9: e51712. doi:10.7554/eLife.51712. ISSN 2050-084X. PMC 7180059. PMID 32252891.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  29. ^ Mirzaei, Mahdieh; Züst, Tobias; Younkin, Gordon C.; Hastings, Amy P.; Alani, Martin L.; Agrawal, Anurag A.; Jander, Georg (2020). "Less Is More: a Mutation in the Chemical Defense Pathway of Erysimum cheiranthoides (Brassicaceae) Reduces Total Cardenolide Abundance but Increases Resistance to Insect Herbivores". Journal of Chemical Ecology. 46 (11–12): 1131–1143. doi:10.1007/s10886-020-01225-y. ISSN 0098-0331.
  30. ^ Alani, Martin L.; Younkin, Gordon C.; Mirzaei, Mahdieh; Kumar, Pavan; Jander, Georg (2021). "Acropetal and basipetal cardenolide transport in Erysimum cheiranthoides (wormseed wallflower)". Phytochemistry. 192: 112965. doi:10.1016/j.phytochem.2021.112965. PMC 8655687. PMID 34610557.{{cite journal}}: CS1 maint: PMC format (link)
  31. ^ Boyle, John H.; Strickler, Susan; Twyford, Alex; Ricono, Angela; Powell, Adrian; Zhang, Jing; Xu, Hongxing; Dalgleish, Harmony J.; Jander, Georg; Agrawal, Anurag A.; Puzey, Joshua R. (2022-02-28). "Temporal matches and mismatches between monarch butterfly and milkweed population changes over the past 12,000 years": 2022.02.25.481796. doi:10.1101/2022.02.25.481796. {{cite journal}}: Cite journal requires |journal= (help)
  32. ^ Feng, Honglin; Acosta-Gamboa, Lucia; Kruse, Lars H.; Tracy, Jake D.; Chung, Seung Ho; Nava Fereira, Alba Ruth; Shakir, Sara; Xu, Hongxing; Sunter, Garry; Gore, Michael A.; Casteel, Clare L.; Moghe, Gaurav D.; Jander, Georg (2022). "Acylsugars protect Nicotiana benthamiana against insect herbivory and desiccation". Plant Molecular Biology. 109 (4–5): 505–522. doi:10.1007/s11103-021-01191-3. ISSN 0167-4412.
  33. ^ Chung, Seung Ho; Bigham, Mahdiyeh; Lappe, Ryan R.; Chan, Barry; Nagalakshmi, Ugrappa; Whitham, Steven A.; Dinesh‐Kumar, Savithramma P.; Jander, Georg (2021). "A sugarcane mosaic virus vector for rapid in planta screening of proteins that inhibit the growth of insect herbivores". Plant Biotechnology Journal. 19 (9): 1713–1724. doi:10.1111/pbi.13585. ISSN 1467-7644. PMC 8428830. PMID 33763921.{{cite journal}}: CS1 maint: PMC format (link)
  34. ^ Rauf, I.; Asif, M.; Amin, I.; Naqvi, R. Z.; Umer, N.; Mansoor, S.; Jander, G. (2019). "Silencing cathepsin L expression reduces Myzus persicae protein content and the nutritional value as prey for Coccinella septempunctata". Insect Molecular Biology. 28 (6): 785–797. doi:10.1111/imb.12589. ISSN 0962-1075.
  35. ^ Chen, Wenbo; Shakir, Sara; Bigham, Mahdiyeh; Richter, Annett; Fei, Zhangjun; Jander, Georg (2019-04-01). "Genome sequence of the corn leaf aphid ( Rhopalosiphum maidis Fitch)". GigaScience. 8 (4). doi:10.1093/gigascience/giz033. ISSN 2047-217X. PMC 6451198. PMID 30953568.{{cite journal}}: CS1 maint: PMC format (link)
  36. ^ Haribal, Meena; Jander, Georg (2015-12-01). "Stable isotope studies reveal pathways for the incorporation of non-essential amino acids in Acyrthosiphon pisum (pea aphids)". Journal of Experimental Biology. 218 (23): 3797–3806. doi:10.1242/jeb.129189. ISSN 1477-9145.
  37. ^ Tzin, Vered; Lindsay, Penelope L.; Christensen, Shawn A.; Meihls, Lisa N.; Blue, Levi B.; Jander, Georg (2015). "Genetic mapping shows intraspecific variation and transgressive segregation for caterpillar‐induced aphid resistance in maize". Molecular Ecology. 24 (22): 5739–5750. doi:10.1111/mec.13418. ISSN 0962-1083.
  38. ^ Casteel, Clare L.; De Alwis, Manori; Bak, Aurélie; Dong, Haili; Whitham, Steven A.; Jander, Georg (2015). "Disruption of Ethylene Responses by Turnip mosaic virus Mediates Suppression of Plant Defense against the Green Peach Aphid Vector". Plant Physiology. 169 (1): 209–218. doi:10.1104/pp.15.00332. ISSN 0032-0889. PMC 4577379. PMID 26091820.{{cite journal}}: CS1 maint: PMC format (link)
  39. ^ Ramsey, John S.; Elzinga, Dezi A.; Sarkar, Pooja; Xin, Yi-Ran; Ghanim, Murad; Jander, Georg (2014). "Adaptation to Nicotine Feeding in Myzus persicae". Journal of Chemical Ecology. 40 (8): 869–877. doi:10.1007/s10886-014-0482-5. ISSN 0098-0331. PMC 4170791. PMID 25082103.{{cite journal}}: CS1 maint: PMC format (link)
  40. ^ Elzinga, Dezi A.; De Vos, Martin; Jander, Georg (2014). "Suppression of Plant Defenses by a Myzus persicae (Green Peach Aphid) Salivary Effector Protein". Molecular Plant-Microbe Interactions®. 27 (7): 747–756. doi:10.1094/MPMI-01-14-0018-R. ISSN 0894-0282. PMC 4170801. PMID 24654979.{{cite journal}}: CS1 maint: PMC format (link)
  41. ^ "About Us". Elo Life Systems. Retrieved 2022-12-24.
  42. ^ "Zymtronix". zymtronix.com. Retrieved 2022-12-24.
  43. ^ "Dezi Elzinga". Dezi Elzinga. 2022-12-24.
  44. ^ "John Ramsey : USDA ARS". www.ars.usda.gov. Retrieved 2022-12-24.
  45. ^ Detrick, Scott (2022-10-19). "Dr. Yann-Ru Lou". Department of Plant Biology. Retrieved 2022-12-24.
  46. ^ "Principal Investigators at AGIS". Principal Investigators at AGIS. 2022-12-24.
  47. ^ "BTI Internships". Boyce Thompson Institute. Retrieved 2022-12-24.
  48. ^ "NSF Award Search: Award # 1850796 - REU Site: Plant Genome Research". nsf.gov. Retrieved 2022-12-24.
  49. ^ "Recent Awards". portal.nifa.usda.gov. Retrieved 2022-12-24.
  50. ^ "Adam-Steinbrenner | UW Biology". www.biology.washington.edu. Retrieved 2022-12-24.
  51. ^ "Kaitlin Gold". CALS. Retrieved 2022-12-24.
  52. ^ "Inari: Home". inari.com. Retrieved 2022-12-24.
  53. ^ "Intern Profiles". Boyce Thompson Institute. Retrieved 2022-12-24.
  54. ^ "Friedrich Wilhelm Bessel Research Award - Research in Germany". www.research-in-germany.org. Retrieved 2022-12-24.
  55. ^ "AAAS Members Elected as Fellows | American Association for the Advancement of Science (AAAS)". www.aaas.org. Retrieved 2022-12-24.
  56. ^ "Fellow of ASPB". American Society of Plant Biologists. Retrieved 2022-12-24.

External links[edit]



Category:Living people Category:Year of birth missing (living people) Category:Cornell University faculty Category:Entomologists Category:Male

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