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Running bibliography for Laryngeal Papillomatosis article[edit]

Barnes, L., UniversitätsSpital Zürich., International Academy of Pathology., World Health Organization., & International Agency for Research on Cancer. (2005). Pathology and genetics of head and neck tumours. Lyon: IARC Press. 

  • Synonyms, epidemiology, localization, clinical features, signs and symptoms

Fletcher, C. D. M. (2013). Diagnostic histopathology of tumors. Philadelphia, PA: Saunders/Elsevier. 

  • Normal anatomy, clinical features

Grimes, J., Fagerberg, K., & Smith, L. (2014). Sexually transmitted disease: An encyclopedia of diseases, prevention, treatment, and issues

  • U.S. epidemiology, viral etiology

Michaels, L., & Hellquist, H. B. (2001). Ear, nose and throat histopathology. London: Springer. 

  • Appearance, differential diagnosis, development, viral etiology

Rubin, J. S., Sataloff, R. T., & Korovin, G. S. (2006). Diagnosis and treatment of voice disorders. San Diego: Plural Pub.

  • Incidence and diagnosis of malignant transformation

Remacle, M., & Eckel, H. E. (2010). Surgery of larynx and trachea. Berlin: Springer. 

  • Management (Surgery, Cidofir)

Sataloff, R. T. (2013). Atlas of laryngoscopy. San Diego, CA: Plural Pub.

  • Laryngoscopy of larynx, excision, videostroboscopy

Wenig, B. M. (2008). Atlas of head and neck pathology. Philadelphia, Pa.: Saunders/Elsevier. 

  • Clinical Features

https://www.nidcd.nih.gov/health/recurrent-respiratory-papillomatosis

  • Concise overview of laryngeal papillomatosis

Plans for Laryngeal Papillomatosis article[edit]

I have identified a number of aspects of improve, including:

  • Better lead section
  • Photo needed
  • Citations are needed more consistently in all sections
  • Better in-text hyperlinks for medical terms/procedures
  • More information on voice therapy
  • Consider renaming "treatment" section to "management" because there is no cure
  • Consider adding an outcomes section
  • Treatment section needs major revision of medical procedures
  • Consider adding an epidemiology section
  • Address the relationship between laryngeal papillomatosis and recurrent respiratory papillomatosis

I personally plan to address the following parts of the article:

  • Contribute to improvement of lead section
  • Add an epidemiology section
  • Edit and add to the diagnosis section as needed

Bibliography to follow. It will also be posted on the article's talk page.

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Synonyms[edit]

Recurrent respiratory papillomatosis, laryngeal papillomatosis, juvenile papillomatosis, adult papillomatosis, squamous cell papilloma, squamous cell papillomatosis.[1]

Squamous papilloma; laryngeal papillomatosis; recurrent respiratory papillomatosis (RRP), juvenile papillomatosis, adult papillomatosis; nonkeratinized papilloma.[2]

Epidemiology[edit]

Laryngeal papillomatosis is a rare disease with a bimodal distribution based on age of incidence.[1] The incidence, or number of new cases, of laryngeal papillomatosis cases is at approximately 4.3 cases per 100 000 children and 1.8 cases per 100 000 adults annually.[1][3][4][5] The incidence of laryngeal papillomatosis in children peaks before the age of 5, though the term juvenile papillomatosis refers to all cases occurring before the age of 20.[1][5] The incidence of adult laryngeal papillomatosis, which has an onset after the age of 20, peaks between the ages of 20 and 40.[1][5] While there are no gender differences in the incidence of laryngeal papillomatosis in children, adult laryngeal papillomatosis occurs more frequently in males than in females.[1][2][5] The incidence of laryngeal papillomatosis also varies according to factors such as socioeconomic status, such that higher rates are observed in groups having a lower socioeconomic status.[5]

Diagnosis[edit]

Laryngeal papillomatosis can be diagnosed through visualization of the lesions using one of several indirect laryngoscopy procedures.[4][6] In indirect laryngoscopy, the tongue is pulled forward and a laryngeal mirror or a rigid scope is passed through the mouth to examine the larynx.[3][4] Another variation of indirect laryngoscopy involves passing a flexible scope, known as a fiberscope or endoscope, through the nose and into the throat to visualize the larynx from above.[3][6] This procedure is also called flexible fiberoptic laryngoscopy.[3]

The appearance of papillomas has been described as multiple or rarely, single, white growths with a lumpy texture similar to cauliflower.[3][5] Papillomas usually present in the larynx, especially on the vocal folds and in the space above the vocal folds called the ventricles.[2][7][1] They can spread to other parts of the larynx and throughout the aerodigestive tract, from the mouth to the lower respiratory tract.[1][5][2] Spread to regions beyond the larynx is more common in children then adults.[2] Growths tend to be located at normal junctions in squamous and ciliated epithelium or at tissue junctions arising from injury.[1][2][7]

A confirmatory diagnosis of laryngeal papillomatosis can only be obtained through a biopsy, involving microscopic examination and HPV testing of a sample of the growth.[5][4] Biopsy samples are collected under general anesthesia, either through direct laryngoscopy or fiberoptic bronchoscopy.[4][5] 

  1. ^ a b c d e f g h i International Agency for Research on Cancer (IARC) (2017). "Tumours of the Hypopharynx, Larynx, Trachea and Parapharyngeal Space". In El-Naggar, Adel K.; Chan, John K. C.; Grandis, Jennifer R.; Takashi, Takata; Slootweg, Pieter J. (eds.). World Health Organization Classification of Head and Neck Tumours. Lyon: International Agency for Research on Cancer. pp. 93–95. ISBN 9789283224389. OCLC 990147303.
  2. ^ a b c d e f Wenig, Bruce M. (2013). "Tumors of the Upper Respiratory Tract". In Fletcher, MD, Christopher D. M. (ed.). Diagnostic Histopathology of Tumors. Fletcher, Christopher D. M., (4th Ed. ed.). Philadelphia, PA: Saunders/Elsevier. pp. 92–98. ISBN 9781455737543. OCLC 846903109. {{cite book}}: |edition= has extra text (help)CS1 maint: extra punctuation (link)
  3. ^ a b c d e Colton, Raymond H.; Casper, Janina K.; Leonard, Rebecca (2011). Understanding Voice Problems : A Physiological Perspective for Diagnosis and Treatment (4th Ed. ed.). Philadelphia, PA: Lippincott Williams & Wilkins. ISBN 9781609138745. OCLC 660546194. {{cite book}}: |edition= has extra text (help)CS1 maint: date and year (link)
  4. ^ a b c d e Grimes, MD, Jill; Fagerberg, MD, Kristyn; Smith, MD, Lori, eds. (2014). "Laryngeal Papillomatosis". Sexually Transmitted Disease : An Encyclopedia of Diseases, Prevention, Treatment, and Issues. Santa Barbara, CA: Greenwood. pp. 401–403. ISBN 9781440801341. OCLC 880530919.{{cite book}}: CS1 maint: date and year (link)
  5. ^ a b c d e f g h i Fortes, Helena Ribeiro; Ranke, Felipe Mussi von; Escuissato, Dante Luiz; Neto, Cesar Augusto Araujo; Zanetti, Gláucia; Hochhegger, Bruno; Souza, Carolina Althoff; Marchiori, Edson. "Recurrent respiratory papillomatosis: A state-of-the-art review". Respiratory Medicine. 126: 116–121. doi:10.1016/j.rmed.2017.03.030.
  6. ^ a b "Recurrent Respiratory Papillomatosis or Laryngeal Papillomatosis". NIDCD. 2015-08-18. Retrieved 2017-10-06.
  7. ^ a b Grant, David G.; Mirchall, Martin A.; Bradley, Patrick J. (2010). "Surgery for Benign Tumors of the Adult Larynx". In Remacle, Marc; Eckel, Hans Edmund (eds.). Surgery of Larynx and Trachea. Berlin: Springer-Verlag Berlin Heidelberg. pp. 91–112. ISBN 9783540791355. OCLC 567327912.