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Julialturner/PAFAH1B1
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From Wikipedia, the free encyclopedia
<
User:Julialturner
Example with long list of GO terms
PAFAH1B1
Available structures
PDB
Human UniProt search:
PDBe
RCSB
List of PDB id codes
1UUJ
,
1VYH
Identifiers
Aliases
PAFAH1B1
, LIS1, LIS2, MDCR, MDS, PAFAH, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa), NudF, platelet activating factor acetylhydrolase 1b regulatory subunit 1
External IDs
OMIM:
601545
HomoloGene:
371
GeneCards:
PAFAH1B1
Genetically Related Diseases
lissencephaly due to LIS1 mutation
[1]
Gene ontology
Molecular function
•
heparin binding
•
phospholipase binding
•
dynactin binding
•
GO:0032403 protein-containing complex binding
•
protein homodimerization activity
•
GO:0001948, GO:0016582 protein binding
•
dynein intermediate chain binding
•
microtubule binding
•
phosphoprotein binding
•
phospholipase A2 activity
•
dynein complex binding
•
microtubule plus-end binding
Cellular component
•
cytoplasm
•
cytosol
•
nuclear membrane
•
nuclear envelope
•
membrane
•
microtubule organizing center
•
perinuclear region of cytoplasm
•
neuron projection
•
microtubule
•
cytoskeleton
•
nucleus
•
kinetochore
•
centrosome
•
astral microtubule
•
microtubule associated complex
•
extracellular exosome
•
kinesin complex
•
microtubule cytoskeleton
•
growth cone
•
spindle
•
axon
•
neuronal cell body
•
cell cortex
•
vesicle
•
cell leading edge
•
axon cytoplasm
•
motile cilium
•
stereocilium
•
central region of growth cone
•
cytoplasmic microtubule
Biological process
•
germ cell development
•
positive regulation of cytokine-mediated signaling pathway
•
neuromuscular process controlling balance
•
nuclear migration
•
microtubule cytoskeleton organization involved in establishment of planar polarity
•
G2/M transition of mitotic cell cycle
•
stem cell division
•
acrosome assembly
•
cell cycle
•
osteoclast development
•
positive regulation of embryonic development
•
microtubule organizing center organization
•
cochlea development
•
platelet activating factor metabolic process
•
GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity
•
adult locomotory behavior
•
transmission of nerve impulse
•
regulation of microtubule cytoskeleton organization
•
positive regulation of cellular component organization
•
positive regulation of mitotic cell cycle
•
protein secretion
•
cortical microtubule organization
•
learning or memory
•
neuroblast proliferation
•
positive regulation of axon extension
•
auditory receptor cell development
•
brain morphogenesis
•
chemical synaptic transmission
•
retrograde axonal transport
•
cell differentiation
•
negative regulation of neuron projection development
•
neuron migration
•
nervous system development
•
cerebral cortex development
•
establishment of centrosome localization
•
ameboidal-type cell migration
•
positive regulation of dendritic spine morphogenesis
•
microtubule cytoskeleton organization
•
actin cytoskeleton organization
•
vesicle transport along microtubule
•
lipid metabolism
•
establishment of planar polarity of embryonic epithelium
•
cell division
•
multicellular organism development
•
lipid catabolic process
•
negative regulation of JNK cascade
•
brain development
•
layer formation in cerebral cortex
•
nuclear membrane disassembly
•
cerebral cortex neuron differentiation
•
corpus callosum morphogenesis
•
hippocampus development
•
cell migration
•
sister chromatid cohesion
•
establishment of mitotic spindle orientation
•
microtubule-based process
•
maintenance of centrosome location
•
ciliary basal body-plasma membrane docking
•
regulation of G2/M transition of mitotic cell cycle
•
GO:0015915 transport
•
microtubule sliding
Sources:
Amigo
/
QuickGO
RNA expression
pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
5048
n/a
Ensembl
ENSG00000007168
n/a
UniProt
P43034
n/a
RefSeq (mRNA)
NM_000430
n/a
RefSeq (protein)
NP_000421
n/a
Location (UCSC)
Chr 17: 2.59 – 2.69 Mb
n/a
PubMed
search
[2]
n/a
Wikidata
View/Edit Human
^
"Diseases that are genetically associated with PAFAH1B1 view/edit references on wikidata"
.
^
"Human PubMed Reference:"
.