User:Kamilaosypiuk/DISC1

Work in progress - we (Kelley Ambrose, Ben Snawder, and myself) will be updating the DISC1 stub. Stay tuned!

Project Proposal

DISC1 protein, encoded by the DISC1 gene, functions in neuronal growth and development. A mutated form of the protein has been linked to a familial case of schizophrenia and may also be implicated in bipolar disorder. Our goals for expanding the DISC1 article include further developing the introductory paragraph, elaborating on the normal function of the protein, its mutation, and the implications of the disrupted protein in mental disorders. As many unanswered questions regarding this topic still remain, our article will also emphasize the current research that is being conducted to increase knowledge about it and past research that has led to the current findings.

Currently, the page has a brief summary of the protein, and topic headings for “Function”, “Clinical Significance”, “Interactions”, “References” and “Further Reading”. We intend to improve it in the following ways (each individual's tasks are outlined in parentheses):

1. Double-check the validity of and add relevant details to the information that is currently on the page. (All)
   1. Visit referenced source pages and verify information is up-to-date.
   2. Explore the source pages in more depth and use them as a first “go-to” for our research
   3. Use databases to verify information: PubMed, PsycINFO, APA PsychNET
2. Add a history section – how it was discovered, studies that were done in discovery (Kelley Ambrose)
3. Add a “Structure and Mechanisms” section (Ben Snawder)
4. Detail the interactions between DISC1 and the listed proteins (Ben Snawder)
5. Broaden and add subtopics under "Clinical Significance" (including but not limited to: Schizophrenia, Bipolar disorder) (Kelley Ambrose and Kamila Osypiuk)
6. Add “Current Research” section (Kamila Osypiuk)