User:Martaak/Non-synaptic plasticity

This is a subpage for the proposal of our project on editing the Wikipedia page for Non-synaptic plasticity.

Main Points[edit]

General Definition[edit]

Non-synaptic plasticity is a form of neuroplasticity that involves modification of ion channel function in the axon, dendrites, and cell body that results in specific changes in the integration of EPSPs and IPSPs, thus modifying the intrinsic excitability of the neuron. It regulates synaptic plasticity, however it is considered separate from synaptic plasticity itself.

Effects on Brain Cell Function[edit]

Synaptic integration
Subthreshold signal propagation
Spike generation
Regulator of Synaptic-Plasticity

Higher Brain Function involved with Non-Synaptic Plasticity[edit]

Long-Term Associative Memory
Learning
Classical conditioning
Homeostatic Regulation

Types of Non-Synaptic Plasticity[edit]

Neuromodulation
Structural Plasticity
Short-Term Plasticity
- Intrinsic Excitability of individual neurons

Non-Synaptic vs Synaptic Plasticity[edit]

Non-Synaptic Plasticity involves modification of neuronal excitability in the axon, dendritic, and somatic areas of an individual neuron, remote from the synapse. Synaptic Plasticity deals directly with the strength of the connection between two neurons, including amount of neurotransmitter released from the pre-synaptic neuron, and the response generated in the post-synaptic neuron.

References[edit]

Division of Workload[edit]

We have agreed to schedule group sessions where we can work together on the various parts of this project. This will result in a cohesive article that best explains our topic.