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User:Mr. Ibrahem/Alcaftadine

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Mr. Ibrahem/Alcaftadine
Clinical data
Trade namesLastacaft
AHFS/Drugs.comMonograph
MedlinePlusa611022
License data
Routes of
administration
Eye drop
Drug classH1 histamine receptor blocker[1]
Legal status
Legal status
Pharmacokinetic data
Onset of actionWithin 3 min[2]
Elimination half-life~2 hrs
Duration of actionUp to 16 hrs[2]
Identifiers
  • 2-(1-Methylpiperidin-4-ylidene)-4,7-diazatricyclo[8.4.0.0(3,7)]tetradeca- 1(14),3,5,10,12-pentaene-6-carbaldehyde
Chemical and physical data
FormulaC19H21N3O
Molar mass307.397 g·mol−1
3D model (JSmol)
  • CN1CCC(=C2c3ccccc3CCn4c(C=O)cnc24)CC1
  • InChI=1S/C19H21N3O/c1-21-9-6-15(7-10-21)18-17-5-3-2-4-14(17)8-11-22-16(13-23)12-20-19(18)22/h2-5,12-13H,6-11H2,1H3 checkY
  • Key:MWTBKTRZPHJQLH-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Alcaftadine, sold under the brand name Lastacaft, is a medication used to treat allergic conjunctivitis.[1] It may be used in those over the age of 1 year.[2] It is used as an eye drop.[1] Benefits occur within 3 minutes and may last for up to 16 hours.[2]

Common side effects include eye irritation, redness, and itchiness.[1] Safety in pregnancy is unclear.[4] It is a H1 histamine receptor blocker.[1]

Alcaftadine was approved for medical use in the United States in 2010.[1] In the United States 3 ml costs about 240 USD as of 2022.[5]

References[edit]

  1. ^ a b c d e f g h "DailyMed - LASTACAFT- alcaftadine solution/ drops". dailymed.nlm.nih.gov. Archived from the original on 27 September 2020. Retrieved 13 January 2022.
  2. ^ a b c d "Alcaftadine Monograph for Professionals". Drugs.com. Archived from the original on 4 March 2021. Retrieved 13 January 2022.
  3. ^ "Alcaftadine ophthalmic (Lastacaft) Use During Pregnancy". Drugs.com. 11 October 2019. Archived from the original on 10 June 2020. Retrieved 10 June 2020.
  4. ^ "Alcaftadine ophthalmic (Lastacaft) Use During Pregnancy". Drugs.com. Archived from the original on 10 June 2020. Retrieved 13 January 2022.
  5. ^ "Alcaftadine Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 13 January 2022.