User:Mr. Ibrahem/Avatrombopag
Clinical data | |
---|---|
Pronunciation | a" va trom' boe pag |
Trade names | Doptelet |
Other names | Avatrombopag maleate |
AHFS/Drugs.com | Monograph |
MedlinePlus | a618032 |
License data |
|
Routes of administration | By mouth |
Drug class | Thrombopoietin receptor agonist[1] |
Legal status | |
Legal status |
|
Identifiers | |
| |
Chemical and physical data | |
Formula | C29H34Cl2N6O3S2 |
Molar mass | 649.65 g·mol−1 |
3D model (JSmol) | |
| |
| |
(what is this?) |
Avatrombopag, sold under the brand name Doptelet, is a medication used to treat low platelets in chronic liver disease when an invasive medical procedure is required.[2][3] It is taken by mouth.[1]
Common side effects include fever, abdominal pain, nausea, headache, tiredness, and peripheral swelling.[2] Other side effects may include blood clots.[2] Use in pregnancy may harm the baby.[2] Safety in pregnancy or breastfeeding is unclear.[1] It is a thrombopoietin receptor agonist, which increases platelet production.[1]
Avatrombopag was approved for medical use in the United States in 2018 and Europe in 2019.[2][3] In the United Kingdom a course of treatment costs the NHS £640 to £960 as of 2020.[4] In the United States this amount is 3,650 USD to 5,500 USD.[5]
References[edit]
- ^ a b c d BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1079. ISBN 978-0857114105.
- ^ a b c d e f g "Avatrombopag Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 16 January 2022.
- ^ a b c d "Doptelet EPAR". European Medicines Agency (EMA). 24 April 2019. Archived from the original on 22 May 2020. Retrieved 2 May 2020.
- ^ "Avatrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure". Archived from the original on 17 January 2022. Retrieved 16 January 2022.
- ^ "Doptelet Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 16 April 2021. Retrieved 16 January 2022.