User:Mr. Ibrahem/Dicycloverine
Clinical data | |
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Trade names | Byclomine, Bentyl, Dibent, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a684007 |
License data | |
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Pharmacokinetic data | |
Protein binding | >99% |
Elimination half-life | 5 h |
Identifiers | |
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Chemical and physical data | |
Formula | C19H35NO2 |
Molar mass | 309.494 g·mol−1 |
3D model (JSmol) | |
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Dicycloverine, also known as dicyclomine, is a medication that is used to treat spasms of the intestines such as occur in irritable bowel syndrome.[2][3] It is taken by mouth or by injection into a muscle.[3] While it has been used in baby colic and enterocolitis, evidence does not support these uses.[3]
Common side effects include dry mouth, blurry vision, weakness, sleepiness, and lightheadedness.[3] Serious side effects may include psychosis and breathing problems in babies.[3] Use in pregnancy appears to be safe while use during breastfeeding is not recommended.[4] How it works is not entirely clear.[3]
Dicycloverine was approved for medical use in the United States in 1950.[3] It is available as a generic medication.[2] In the United Kingdom the NHS pays about 1.84 £ per dose as of 2019.[2] In the United States the wholesale cost of this amount is about US$0.15.[5] In 2017, it was the 181st most commonly prescribed medication in the United States, with more than three million prescriptions.[6][7]
References[edit]
- ^ "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 20 September 2020. Retrieved 7 September 2020.
- ^ a b c British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 759. ISBN 9780857113382.
- ^ a b c d e f g "Dicyclomine Hydrochloride Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Archived from the original on 5 May 2019. Retrieved 3 March 2019.
- ^ "Dicyclomine Pregnancy and Breastfeeding Warnings". Drugs.com. Archived from the original on 6 March 2019. Retrieved 3 March 2019.
- ^ "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services. Archived from the original on 2019-03-06. Retrieved 3 March 2019.
- ^ "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
- ^ "Dicyclomine Hydrochloride - Drug Usage Statistics". ClinCalc. Archived from the original on 12 July 2020. Retrieved 11 April 2020.