User:Mr. Ibrahem/Pramocaine

Mr. Ibrahem/Pramocaine
Clinical data
Trade names	Analpram, Fleet Pain-Relief, Itch-X, Preparation H, others
Other names	Pramoxine, pramoxine HCI
AHFS/Drugs.com	Monograph
MedlinePlus	a682429
Routes of; administration	Topical, rectal, Vaginal
Legal status
Legal status	Depends on country, some formulations OTC others Rx only;
Identifiers
	IUPAC name 4-[3-(4-Butoxyphenoxy)propyl]morpholine;
Chemical and physical data
Formula	C17H27NO3
Molar mass	293.407 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O(c2ccc(OCCCN1CCOCC1)cc2)CCCC;
	InChI InChI=1S/C17H27NO3/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18/h5-8H,2-4,9-15H2,1H3 ; Key:DQKXQSGTHWVTAD-UHFFFAOYSA-N ;
	(what is this?) (verify)

Pramocaine, also known as pramoxine, is a medication used to improve pain and itching such as occurs in hemorrhoids or insect bites.^[1]^[2] It is applied to the skin.^[1] There are versions that come mixed with corticosteroids.^[1]

Common side effects include burning at the site of application.^[1] Other side effects may include allergic reactions, though it is generally safe even if someone has reactions to other local anesthetics.^[1] It works by stabilizing the cell membrane of neurons.^[1]

Pramocaine was described in 1953.^[3] It is available over the counter.^[1] In the United States a bottle costs about 5 USD as of 2021.^[4]

References[edit]

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ "Pramoxine Monograph for Professionals". Drugs.com. Archived from the original on March 4, 2021. Retrieved October 29, 2021.
^ ^a ^b BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 103. ISBN 978-0857114105.
^ SCHMIDT, JL; BLOCKUS, LE; RICHARDS, RK (November 1953). "The pharmacology of pramoxine hydrochloride: a new topical local anesthetic". Current researches in anesthesia & analgesia. 32 (6:1): 418–25. PMID 13107298.
^ "Compare Pramoxine Hcl Prices - GoodRx". GoodRx. Retrieved October 29, 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ "Pramoxine Monograph for Professionals". Drugs.com. Archived from the original on March 4, 2021. Retrieved October 29, 2021.

[BNF81-2] BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 103. ISBN 978-0857114105.

[Sch1953-3] SCHMIDT, JL; BLOCKUS, LE; RICHARDS, RK (November 1953). "The pharmacology of pramoxine hydrochloride: a new topical local anesthetic". Current researches in anesthesia & analgesia. 32 (6:1): 418–25. PMID 13107298.

[4] "Compare Pramoxine Hcl Prices - GoodRx". GoodRx. Retrieved October 29, 2021.

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