User:Mr. Ibrahem/Suramin
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Trade names | Antrypol, 309 Fourneau, Bayer 205, others |
AHFS/Drugs.com | Drugs.com archive |
Routes of administration | By injection only |
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Chemical and physical data | |
Formula | C51H40N6O23S6 |
Molar mass | 1297.26 g·mol−1 |
3D model (JSmol) | |
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Suramin is a medication used to treat African sleeping sickness and river blindness.[1][3] It is the treatment of choice for sleeping sickness without central nervous system involvement.[4] It is given by injection into a vein.[5]
Suramin causes a fair number of side effects.[5] Common side effects include nausea, vomiting, diarrhea, headache, skin tingling, and weakness.[3] Sore palms of the hands and soles of the feet, trouble seeing, fever, and abdominal pain may also occur.[3] Severe side effects may include low blood pressure, decreased level of consciousness, kidney problems, and low blood cell levels.[5] It is unclear if it is safe when breastfeeding.[3]
Suramin was made at least as early as 1916.[6] It is on the World Health Organization's List of Essential Medicines.[7] In the United States it can be acquired from the Centers for Disease Control (CDC).[4] The cost of the medication for a course of treatment is about US$27.[8] In regions of the world where the disease is common suramin is provided for free by the World Health Organization (WHO).[9]
References[edit]
- ^ a b "Suramin Injection Advanced Patient Information". Drugs.com. 3 January 2020. Archived from the original on 8 November 2016. Retrieved 11 January 2020.
- ^ "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 20 September 2020. Retrieved 4 September 2020.
- ^ a b c d "Micromedex Detailed Drug Information for the Consumer: Suramin (Injection route)". PubMed Health. 1 November 2016. Archived from the original on 8 September 2017.
- ^ a b "Our Formulary Infectious Diseases Laboratories CDC". www.cdc.gov. 22 September 2016. Archived from the original on 16 December 2016. Retrieved 30 November 2016.
- ^ a b c Zuckerman, Dr Jane N. (2002). Principles and Practice of Travel Medicine. John Wiley & Sons. p. 113. ISBN 9780471490791. Archived from the original on 2016-11-30.
- ^ Mehlhorn, Heinz (2008). Encyclopedia of Parasitology: A-M. Springer Science & Business Media. p. 475. ISBN 9783540489948. Archived from the original on 2016-11-30.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ Dumas, Michel; Bouteille, Bernard; Buguet, Alain (2013). Progress in Human African Trypanosomiasis, Sleeping Sickness. Springer Science & Business Media. p. 256. ISBN 9782817808574. Archived from the original on 2016-11-30.
- ^ "Trypanosomiasis, human African (sleeping sickness)". World Health Organization. February 2016. Archived from the original on 4 December 2016. Retrieved 7 December 2016.