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User:Paige1.0/sandbox

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This is my first use of sandbox!

Improving an existing article:

The important thing about this rotavirus article is that it is a featured article on Wikipedia (surprise for me). This means that I posted my comments in the talk page, but I won't change anything to the article unless the is consensus among editors that the information I offered should be added.

faecal-oral route: going to change to “fecal-oral route” since it links to a page titled the same. (((((11.11.16: I will not actually change this because there is a linked article saying that the reason it and other words are spelled this way is because of British terminology. They must have had problems in the past with people changing things)))))

The top heading on the virus under species lists Species A through H, but in the section titled “Epidemiology” only Rotavirus A, B, and C are mentioned. I would like to find articles talking about some of these other types of rotavirus.

I found that Group A, B, and C have been found in humans and other mammals while Group E has been detected only in pigs and Groups D, F, and G have been found only in birds[1]. This could be added to "Other Animals" section as well.

The article states: “Almost every child has been infected with rotavirus by age five” and then cited an article that says nothing of the sort. Rather, this article examined literature published 2000-2004 about rotavirus cases in children and found that the proportion of diarrheal hospitalizations due to rotavirus have increased between the observed years[2]. This orginal citation is important to fix since the claim has no foundation in literature.

11.11.16:

I realized that there wasn’t really a gap in the knowledge for what I wanted to write about for rotavirus. Both Marissa and Cloe suggested that I find articles on the other sources of rotavirus that I talked about on my talk page. I could choose from rotavirus D, E, F, G, and H.

Little is known about groups E-G, which is why there is not much written on the rotavirus page about these specific strains. I decided to work on rotavirus E which infects pigs because I enjoy learning about the intersection between disease, society, and agriculture.

Please see what I plan to post on the rotavirus page to add to the communal knowledge about rotavirus, specifically about rotavirus in pigs.

“Control of rotavirus is important for pork production worldwide not only because of the high rate of high mortality but also considerable rates of co-infection with other diseases. The virus can be detected using a polyacrilamide gel electrophoresis (PAGE) test[3]. Damage to the gut wall is a confirmation of a pig’s infection with rotavirus. Specifically, villi lining the wall of the small intestine become stunted and flattened , a process often called villus atrophy[4]. Additionally, a prevalent symptom is severe diarrhoea (termed 'scours' in livestock) and is especially threatening in piglets less than 5 days of age[5].”

1.      White, Mark. "PigHealth-RotaviralDiarrhoea." NADIS Animal Health, 2016. Web. 11 Nov. 2016.

2.      Pearson, G.r., and M.s. Mcnulty. "Pathological Changes in the Small Intestine of Neonatal Pigs Infected with a Pig Reovirus-like Agent (rotavirus)." Journal of Comparative Pathology 87.3 (1977): 363-75. Web.

E H Bohl, L J Saif, K W Theil, A G Agnes and R F Cross. Porcine pararotavirus: detection, differentiation from rotavirus, and pathogenesis in gnotobiotic pigs. Journal of Clinical Microbiology. 15.2. 1982. 312-319. Web.

Bibliography:

1) http://jvi.asm.org/content/84/19/10254.full#xref-ref-62-1

2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373114/

  1. ^ Trojnar, Eva; Otto, Peter; Roth, Bernhard; Reetz, Jochen; Johne, Reimar (2010-10-01). "The Genome Segments of a Group D Rotavirus Possess Group A-Like Conserved Termini but Encode Group-Specific Proteins". Journal of Virology. 84 (19): 10254–10265. doi:10.1128/JVI.00332-10. ISSN 0022-538X.
  2. ^ Parashar, Umesh D.; Gibson, Christopher J.; Bresee, Joseph S.; Glass, Roger I. (2016-10-12). "Rotavirus and Severe Childhood Diarrhea". Emerging Infectious Diseases. 12 (2): 304–306. doi:10.3201/eid1202.050006. ISSN 1080-6040.
  3. ^ White, Mark (2016). "Pig Health - Rotaviral Diarrhoea". National Animal Disease Information Service. Retrieved November 11, 2016.
  4. ^ Pearson, G. R.; McNulty, M. S. (1977-07-01). "Pathological changes in the small intestine of neonatal pigs infected with a pig reovirus-like agent (rotavirus)". Journal of Comparative Pathology. 87 (3): 363–375. doi:10.1016/0021-9975(77)90026-3.
  5. ^ Bohl, E. H.; Saif, L. J.; Theil, K. W.; Agnes, A. G.; Cross, R. F. (1982-02-01). "Porcine pararotavirus: detection, differentiation from rotavirus, and pathogenesis in gnotobiotic pigs". Journal of Clinical Microbiology. 15 (2): 312–319. ISSN 0095-1137. PMC 272083. PMID 6279693.