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Log file for Protein Box Bot

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Log page index: User:ProteinBoxBot/PBB_Log_Index

Protein Status Quick Log - Date: 20:33, 20 December 2007 (UTC)

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Proteins with a High Potential Match (1)

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HSPA8

Redirected Proteins (11)

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HNRPK HPRT1 HMGA1 HSPA9 HMMR
HDAC2 HNRPAB HSPA2 HDAC1 APEX1
HMGB1

Manual Inspection (Page not found) (1)

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HSPA8

Updated (11)

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HNRPK HPRT1 HMGA1 HSPA9 HMMR
HDAC2 HNRPAB HSPA2 HDAC1 APEX1
HMGB1


Protein Status Grid - Date: 20:33, 20 December 2007 (UTC)

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HUGO Symbol Action Summary Target page(s) WP Symbol Search
HNRPK Updated Location: HNRPK; [1]
HPRT1 Updated Location: Hypoxanthine-guanine phosphoribosyltransferase; [2]
HMGA1 Updated Location: HMGA1; [3]
HSPA9 Updated Location: HSPA9; [4]
HSPA8 Manual Inspection (Page not found) Other Pages: Heat shock 70kDa protein 8 (No Data); HSPA8 (No Data); LAP1 (No Data); Lap1 (No Data); HSC54 (No Data); Hsc54 (No Data); HSC70 (No Data); Hsc70 (Protein Template); HSC71 (No Data); Hsc71 (No Data); HSP71 (No Data); Hsp71 (No Data); HSP73 (No Data); Hsp73 (No Data); HSPA10 (No Data); Hspa10 (No Data); MGC131511 (No Data); Mgc131511 (No Data); MGC29929 (No Data); Mgc29929 (No Data); NIP71 (No Data); Nip71 (No Data); [5]
HMMR Updated Location: HMMR; [6]
HDAC2 Updated Location: HDAC2; [7]
HNRPAB Updated Location: HNRPAB; [8]
HSPA2 Updated Location: HSPA2; [9]
HDAC1 Updated Location: HDAC1; [10]
APEX1 Updated Location: APEX1; [11]
HMGB1 Updated Location: HMGB1; [12]

Vebose Log - Date: 20:33, 20 December 2007 (UTC)

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APEX1

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  • INFO: Beginning work on APEX1... {December 20, 2007 12:27:43 PM PST}
  • REDIRECT: Protein Redirected to: APEX1 {December 20, 2007 12:28:15 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:28:16 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:28:16 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:28:16 PM PST}
  • UPDATED: Updated protein page: APEX1 {December 20, 2007 12:28:22 PM PST}

HDAC1

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  • INFO: Beginning work on HDAC1... {December 20, 2007 12:28:22 PM PST}
  • REDIRECT: Protein Redirected to: HDAC1 {December 20, 2007 12:29:04 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:29:06 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:29:06 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:29:06 PM PST}
  • UPDATED: Updated protein page: HDAC1 {December 20, 2007 12:29:13 PM PST}

HDAC2

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  • INFO: Beginning work on HDAC2... {December 20, 2007 12:29:13 PM PST}
  • REDIRECT: Protein Redirected to: HDAC2 {December 20, 2007 12:29:43 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:29:46 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:29:46 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:29:46 PM PST}
  • UPDATED: Updated protein page: HDAC2 {December 20, 2007 12:29:52 PM PST}

HMGA1

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  • INFO: Beginning work on HMGA1... {December 20, 2007 12:30:40 PM PST}
  • REDIRECT: Protein Redirected to: HMGA1 {December 20, 2007 12:30:59 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:31:02 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:31:02 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:31:02 PM PST}
  • UPDATED: Updated protein page: HMGA1 {December 20, 2007 12:31:08 PM PST}

HMGB1

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  • INFO: Beginning work on HMGB1... {December 20, 2007 12:29:52 PM PST}
  • REDIRECT: Protein Redirected to: HMGB1 {December 20, 2007 12:30:30 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:30:32 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:30:32 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:30:32 PM PST}
  • UPDATED: Updated protein page: HMGB1 {December 20, 2007 12:30:39 PM PST}

HMMR

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  • INFO: Beginning work on HMMR... {December 20, 2007 12:31:08 PM PST}
  • REDIRECT: Protein Redirected to: HMMR {December 20, 2007 12:31:27 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:31:29 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:31:29 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:31:29 PM PST}
  • UPDATED: Updated protein page: HMMR {December 20, 2007 12:31:35 PM PST}

HNRPAB

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  • INFO: Beginning work on HNRPAB... {December 20, 2007 12:31:35 PM PST}
  • REDIRECT: Protein Redirected to: HNRPAB {December 20, 2007 12:31:53 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:31:56 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:31:56 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:31:56 PM PST}
  • UPDATED: Updated protein page: HNRPAB {December 20, 2007 12:32:03 PM PST}

HNRPK

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  • INFO: Beginning work on HNRPK... {December 20, 2007 12:32:03 PM PST}
  • REDIRECT: Protein Redirected to: HNRPK {December 20, 2007 12:32:22 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:32:24 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:32:24 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:32:24 PM PST}
  • UPDATED: Updated protein page: HNRPK {December 20, 2007 12:32:30 PM PST}

HPRT1

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  • INFO: Beginning work on HPRT1... {December 20, 2007 12:32:30 PM PST}
  • REDIRECT: Protein Redirected to: Hypoxanthine-guanine phosphoribosyltransferase {December 20, 2007 12:32:48 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:32:49 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:32:49 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:32:49 PM PST}
  • UPDATED: Updated protein page: Hypoxanthine-guanine phosphoribosyltransferase {December 20, 2007 12:32:56 PM PST}

HSPA2

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  • INFO: Beginning work on HSPA2... {December 20, 2007 12:32:56 PM PST}
  • REDIRECT: Protein Redirected to: HSPA2 {December 20, 2007 12:33:15 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:33:16 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:33:16 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:33:16 PM PST}
  • UPDATED: Updated protein page: HSPA2 {December 20, 2007 12:33:23 PM PST}

HSPA8

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  • INFO: Beginning work on HSPA8... {December 20, 2007 12:33:23 PM PST}
  • REDIRECT: Page directory gave bad page (Hsc70). Continuing with search.. Please correct entry: <3312,Hsc70>. {December 20, 2007 12:33:55 PM PST}
  • AMBIGUITY: Did not locate an acceptable page to update. {December 20, 2007 12:34:36 PM PST} 
 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image = PBB_Protein_HSPA8_image.jpg
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1atr.
 | PDB = {{PDB2|1atr}}, {{PDB2|1ats}}, {{PDB2|1ba0}}, {{PDB2|1ba1}}, {{PDB2|1bup}}, {{PDB2|1ckr}}, {{PDB2|1hpm}}, {{PDB2|1hx1}}, {{PDB2|1kax}}, {{PDB2|1kay}}, {{PDB2|1kaz}}, {{PDB2|1nga}}, {{PDB2|1ngb}}, {{PDB2|1ngc}}, {{PDB2|1ngd}}, {{PDB2|1nge}}, {{PDB2|1ngf}}, {{PDB2|1ngg}}, {{PDB2|1ngh}}, {{PDB2|1ngi}}, {{PDB2|1ngj}}, {{PDB2|1qqm}}, {{PDB2|1qqn}}, {{PDB2|1qqo}}, {{PDB2|1ud0}}, {{PDB2|1yuw}}, {{PDB2|2bup}}, {{PDB2|3hsc}}, {{PDB2|7hsc}}
 | Name = Heat shock 70kDa protein 8
 | HGNCid = 5241
 | Symbol = HSPA8
 | AltSymbols =; LAP1; HSC54; HSC70; HSC71; HSP71; HSP73; HSPA10; MGC131511; MGC29929; NIP71
 | OMIM = 600816
 | ECnumber =  
 | Homologene = 68524
 | MGIid = 105384
 | GeneAtlas_image1 = PBB_GE_HSPA8_210338_s_at_tn.png
 | GeneAtlas_image2 = PBB_GE_HSPA8_208687_x_at_tn.png
 | GeneAtlas_image3 = PBB_GE_HSPA8_221891_x_at_tn.png
 | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0042623 |text = ATPase activity, coupled}} 
 | Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0009986 |text = cell surface}} 
 | Process = {{GNF_GO|id=GO:0006457 |text = protein folding}} {{GNF_GO|id=GO:0006986 |text = response to unfolded protein}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3312
    | Hs_Ensembl = ENSG00000109971
    | Hs_RefseqProtein = NP_006588
    | Hs_RefseqmRNA = NM_006597
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 11
    | Hs_GenLoc_start = 122433411
    | Hs_GenLoc_end = 122438054
    | Hs_Uniprot = P11142
    | Mm_EntrezGene = 15481
    | Mm_Ensembl =  
    | Mm_RefseqmRNA = NM_031165
    | Mm_RefseqProtein = NP_112442
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr =  
    | Mm_GenLoc_start =  
    | Mm_GenLoc_end =  
    | Mm_Uniprot =  
  }}
}}
'''Heat shock 70kDa protein 8''', also known as '''HSPA8''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HSPA8 heat shock 70kDa protein 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3312| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.<ref name="entrez">{{cite web | title = Entrez Gene: HSPA8 heat shock 70kDa protein 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3312| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Kiang JG |title=Inducible heat shock protein 70 kD and inducible nitric oxide synthase in hemorrhage/resuscitation-induced injury. |journal=Cell Res. |volume=14 |issue= 6 |pages= 450-9 |year= 2005 |pmid= 15625011 |doi= 10.1038/sj.cr.7290247 }}
*{{cite journal  | author=Rasmussen HH, van Damme J, Puype M, ''et al.'' |title=Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 960-9 |year= 1993 |pmid= 1286667 |doi=  }}
*{{cite journal  | author=Hattori H, Liu YC, Tohnai I, ''et al.'' |title=Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells. |journal=Cell Struct. Funct. |volume=17 |issue= 1 |pages= 77-86 |year= 1992 |pmid= 1586970 |doi=  }}
*{{cite journal  | author=DeLuca-Flaherty C, McKay DB, Parham P, Hill BL |title=Uncoating protein (hsc70) binds a conformationally labile domain of clathrin light chain LCa to stimulate ATP hydrolysis. |journal=Cell |volume=62 |issue= 5 |pages= 875-87 |year= 1990 |pmid= 1975516 |doi=  }}
*{{cite journal  | author=Lim MY, Davis N, Zhang JY, Bose HR |title=The v-rel oncogene product is complexed with cellular proteins including its proto-oncogene product and heat shock protein 70. |journal=Virology |volume=175 |issue= 1 |pages= 149-60 |year= 1990 |pmid= 2155506 |doi=  }}
*{{cite journal  | author=Welch WJ, Mizzen LA |title=Characterization of the thermotolerant cell. II. Effects on the intracellular distribution of heat-shock protein 70, intermediate filaments, and small nuclear ribonucleoprotein complexes. |journal=J. Cell Biol. |volume=106 |issue= 4 |pages= 1117-30 |year= 1988 |pmid= 2966179 |doi=  }}
*{{cite journal  | author=Dworniczak B, Mirault ME |title=Structure and expression of a human gene coding for a 71 kd heat shock 'cognate' protein. |journal=Nucleic Acids Res. |volume=15 |issue= 13 |pages= 5181-97 |year= 1987 |pmid= 3037489 |doi=  }}
*{{cite journal  | author=Rensing SA, Maier UG |title=Phylogenetic analysis of the stress-70 protein family. |journal=J. Mol. Evol. |volume=39 |issue= 1 |pages= 80-6 |year= 1994 |pmid= 7545947 |doi=  }}
*{{cite journal  | author=Lain B, Iriarte A, Mattingly JR, ''et al.'' |title=Structural features of the precursor to mitochondrial aspartate aminotransferase responsible for binding to hsp70. |journal=J. Biol. Chem. |volume=270 |issue= 42 |pages= 24732-9 |year= 1995 |pmid= 7559589 |doi=  }}
*{{cite journal  | author=Benaroudj N, Batelier G, Triniolles F, Ladjimi MM |title=Self-association of the molecular chaperone HSC70. |journal=Biochemistry |volume=34 |issue= 46 |pages= 15282-90 |year= 1995 |pmid= 7578144 |doi=  }}
*{{cite journal  | author=Nunes SL, Calderwood SK |title=Heat shock factor-1 and the heat shock cognate 70 protein associate in high molecular weight complexes in the cytoplasm of NIH-3T3 cells. |journal=Biochem. Biophys. Res. Commun. |volume=213 |issue= 1 |pages= 1-6 |year= 1995 |pmid= 7639722 |doi= 10.1006/bbrc.1995.2090 }}
*{{cite journal  | author=Inoue A, Torigoe T, Sogahata K, ''et al.'' |title=70-kDa heat shock cognate protein interacts directly with the N-terminal region of the retinoblastoma gene product pRb. Identification of a novel region of pRb-mediating protein interaction. |journal=J. Biol. Chem. |volume=270 |issue= 38 |pages= 22571-6 |year= 1995 |pmid= 7673249 |doi=  }}
*{{cite journal  | author=Abe T, Konishi T, Hirano T, ''et al.'' |title=Possible correlation between DNA damage induced by hydrogen peroxide and translocation of heat shock 70 protein into the nucleus. |journal=Biochem. Biophys. Res. Commun. |volume=206 |issue= 2 |pages= 548-55 |year= 1995 |pmid= 7826371 |doi= 10.1006/bbrc.1995.1078 }}
*{{cite journal  | author=Furlini G, Vignoli M, Re MC, ''et al.'' |title=Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein. |journal=J. Gen. Virol. |volume=75 ( Pt 1) |issue=  |pages= 193-9 |year= 1994 |pmid= 7906708 |doi=  }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | author=Tavaria M, Gabriele T, Anderson RL, ''et al.'' |title=Localization of the gene encoding the human heat shock cognate protein, HSP73, to chromosome 11. |journal=Genomics |volume=29 |issue= 1 |pages= 266-8 |year= 1996 |pmid= 8530083 |doi= 10.1006/geno.1995.1242 }}
*{{cite journal  | author=Gao B, Eisenberg E, Greene L |title=Effect of constitutive 70-kDa heat shock protein polymerization on its interaction with protein substrate. |journal=J. Biol. Chem. |volume=271 |issue= 28 |pages= 16792-7 |year= 1996 |pmid= 8663341 |doi=  }}
*{{cite journal  | author=Egerton M, Moritz RL, Druker B, ''et al.'' |title=Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. |journal=Biochem. Biophys. Res. Commun. |volume=224 |issue= 3 |pages= 666-74 |year= 1996 |pmid= 8713105 |doi= 10.1006/bbrc.1996.1082 }}
*{{cite journal  | author=Lamian V, Small GM, Feldherr CM |title=Evidence for the existence of a novel mechanism for the nuclear import of Hsc70. |journal=Exp. Cell Res. |volume=228 |issue= 1 |pages= 84-91 |year= 1996 |pmid= 8892974 |doi= 10.1006/excr.1996.0302 }}
*{{cite journal  | author=Hansen S, Midgley CA, Lane DP, ''et al.'' |title=Modification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70. |journal=J. Biol. Chem. |volume=271 |issue= 48 |pages= 30922-8 |year= 1997 |pmid= 8940078 |doi=  }}
}}
{{refend}}

{{protein-stub}}

HSPA9

[edit]
  • INFO: Beginning work on HSPA9... {December 20, 2007 12:34:36 PM PST}
  • REDIRECT: Protein Redirected to: HSPA9 {December 20, 2007 12:34:51 PM PST}
  • UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 12:34:55 PM PST}
  • UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 12:34:55 PM PST}
  • UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 12:34:55 PM PST}
  • UPDATED: Updated protein page: HSPA9 {December 20, 2007 12:35:02 PM PST}

end log.

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