User talk:Anilapuli
| This user is a student editor in Florida_Institute_of_Technology/Molecular_Genetics_(Fall_2023) . |
Welcome![edit]
Hello, Anilapuli, and welcome to Wikipedia! My name is Ian and I work with Wiki Education; I help support students who are editing as part of a class assignment.
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If you have any questions, please don't hesitate to contact me on my talk page. Ian (Wiki Ed) (talk) 17:57, 30 August 2023 (UTC)
DNA Repair[edit]
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.[1] In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day.[2] Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).[3][4] This can eventually lead to malignant tumors, or cancer as per the two hit hypothesis.
- ^ "Nature Reviews Series: DNA damage". Nature Reviews Molecular Cell Biology. 5 Jul 2017. Retrieved 7 Nov 2018.
- ^ Lodish H, Berk A, Matsudaira P, Kaiser CA, Krieger M, Scott MP, Zipursky SL, Darnell J (2004). Molecular Biology of the Cell (5th ed.). New York: WH Freeman. p. 963.
- ^ Acharya PV (1971). "The isolation and partial characterization of age-correlated oligo-deoxyribo-ribonucleotides with covalently linked aspartyl-glutamyl polypeptides". Johns Hopkins Medical Journal. Supplement (1): 254–60. PMID 5055816.
- ^ Bjorksten J, Acharya PV, Ashman S, Wetlaufer DB (July 1971). "Gerogenic fractions in the tritiated rat". Journal of the American Geriatrics Society. 19 (7): 561–74. doi:10.1111/j.1532-5415.1971.tb02577.x. PMID 5106728. S2CID 33154242.
Anilapuli (talk) 02:24, 5 September 2023 (UTC)
March 2024[edit]
Welcome, and thank you for your attempt to lighten up Wikipedia. However, this is an encyclopedia, and articles are intended to be serious, so please don't make joke edits, as you did to Chromosome abnormality. Readers looking for accurate information will not find them amusing. If you'd like to experiment with editing, please use your sandbox instead, where you are given a certain degree of freedom in what you write. Flounder fillet (talk) 02:17, 19 March 2024 (UTC)