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Villin 1

From Wikipedia, the free encyclopedia
VIL1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesVIL1, D2S1471, VIL, villin 1
External IDsOMIM: 193040; MGI: 98930; HomoloGene: 5169; GeneCards: VIL1; OMA:VIL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007127

NM_009509

RefSeq (protein)

NP_009058

NP_033535

Location (UCSC)Chr 2: 218.42 – 218.45 MbChr 1: 74.45 – 74.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Villin 1 is a protein that in humans is encoded by the VIL1 gene. <ref name="entrez {{cite web | title = Entrez Gene: Villin 1 | url = https://www.ncbi.nlm.nih.gov/gene/7429 | access-date = 2018-09-27 }}</ref>

Function

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This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000127831Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026175Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.