Virapinib

Virapinib
Identifiers
	IUPAC name [3-[7-methyl-4-(methylamino)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]pyrrolidin-1-yl]-[4-(4-methylpiperidin-1-yl)phenyl]methanone;
CAS Number	1794091-10-3;
PubChem CID	127251916;
ChemSpider	29964516;
Chemical and physical data
Formula	C26H36N6O
Molar mass	448.615 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1CCN(CC1)C2=CC=C(C=C2)C(=O)N3CCC(C3)C4=NC5=C(CCN(C5)C)C(=N4)NC;
	InChI InChI=1S/C26H36N6O/c1-18-8-13-31(14-9-18)21-6-4-19(5-7-21)26(33)32-15-10-20(16-32)24-28-23-17-30(3)12-11-22(23)25(27-2)29-24/h4-7,18,20H,8-17H2,1-3H3,(H,27,28,29); Key:LUAVWTOZVHIDSI-UHFFFAOYSA-N;

Virapinib is an antiviral drug which is the first drug developed that acts by inhibiting viral entry into cells via macropinocytosis. While it is only in early developmental stages, initial testing showed broad spectrum antiviral activity against a range of viruses including SARS-CoV-2, Monkeypox virus, Ebolavirus and tick-borne encephalitis virus.^[1]

References

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