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WAC (gene)

From Wikipedia, the free encyclopedia
WAC
Identifiers
AliasesWAC, BM-016, PRO1741, Wwp4, DESSH, WW domain containing adaptor with coiled-coil
External IDsOMIM: 615049; MGI: 2387357; HomoloGene: 41148; GeneCards: WAC; OMA:WAC - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016628
NM_100264
NM_100486

NM_001146298
NM_001282093
NM_153085
NM_001360956

RefSeq (protein)

NP_057712
NP_567822
NP_567823

NP_001139770
NP_001269022
NP_694725
NP_001347885

Location (UCSC)Chr 10: 28.53 – 28.62 MbChr 18: 7.87 – 7.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

WW domain-containing adapter protein with coiled-coil is a protein that in humans is encoded by the WAC gene.[5][6]

The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000095787Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024283Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Xu GM, Arnaout MA (Feb 2002). "WAC, a novel WW domain-containing adapter with a coiled-coil region, is colocalized with splicing factor SC35". Genomics. 79 (1): 87–94. doi:10.1006/geno.2001.6684. PMID 11827461.
  6. ^ a b "Entrez Gene: WAC WW domain containing adaptor with coiled-coil".

Further reading

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