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ZFYVE26

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ZFYVE26
Identifiers
AliasesZFYVE26, FYVE-CENT, SPG15, zinc finger FYVE-type containing 26
External IDsOMIM: 612012; MGI: 1924767; HomoloGene: 9102; GeneCards: ZFYVE26; OMA:ZFYVE26 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015346

NM_001008550

RefSeq (protein)

NP_056161

NP_001008550

Location (UCSC)Chr 14: 67.73 – 67.82 MbChr 12: 79.28 – 79.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger, FYVE domain containing 26 is a protein that in humans is encoded by the ZFYVE26 gene.[5]

Function

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This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000072121Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066440Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: Zinc finger, FYVE domain containing 26".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.