User:Mr. Ibrahem/Cavernous sinus thrombosis

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Cavernous sinus thrombosis
Oblique section through the cavernous sinus.
SpecialtyNeurology
SymptomsHeadache, eye pain, bulging eyes, fever, double vision[1]
ComplicationsMeningitis, brain abscess, pituitary insufficiency[2]
TypesSeptic (infection), aseptic (no infection)[3]
Risk factorsBoil of the nose, sinusitis, dental infection, injury, surgery, easy blood clot formation[3][2]
Diagnostic methodCT scan or MRI[2]
Differential diagnosisCarotid cavernous fistula, meningioma, orbital cellulitis[3]
TreatmentAntibiotics, heparin, corticosteroids, surgery[1]
FrequencyRare[1]
DeathsUp to 30% die[1]

Cavernous sinus thrombosis (CST) is the formation of a blood clot within the cavernous sinus, a cavity at the base of the brain which drains blood from the brain back to the heart.[1] Symptoms may include headache, eye pain, bulging eyes, fever, and double vision.[1] Often one eye is involved initially followed by involvement of the second eye.[3] Complications may include meningitis, brain abscess, and pituitary insufficiency.[2]

There are two types–septic (infection) and aseptic (not infection).[3] Risk factors include infections of the face such as boils on the nose, sinusitis, and dental infections.[2] The bacteria most commonly involved include Staphylococcus aureus and Streptococcus.[2] Other risk factors include injury, surgery, and easy blood clot formation.[3] Diagnosis is generally based on either CT scan or MRI.[2] It is a type of cerebral venous sinus thrombosis.[3]

It is a medical emergency.[1] Treatment may include antibiotics, heparin, and corticosteroids.[1] Occasionally surgery is required to drain an abscess the contributed to the condition.[1][3] Up to 30% of people die, despite treatment.[1] Among those who survive vision loss and seizures may occur.[1] Cavernous sinus thrombosis is rare, affecting possibly 0.2 to 1.6 people per 100,000 per year.[1][3]

References[edit]

  1. ^ a b c d e f g h i j k l "Cavernous sinus thrombosis". nhs.uk. 14 May 2018. Archived from the original on 10 October 2017. Retrieved 7 April 2022.
  2. ^ a b c d e f g "Cavernous Sinus Thrombosis - Eye Disorders". Merck Manuals Professional Edition. Archived from the original on 30 October 2021. Retrieved 7 April 2022.
  3. ^ a b c d e f g h i Plewa, MC; Tadi, P; Gupta, M (January 2022). "Cavernous Sinus Thrombosis". PMID 28846357. {{cite journal}}: Cite journal requires |journal= (help)